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Metalloprotease which may be important for placentation by regulating biological activity of key peptides at the embryo-maternal interface. On synthetic substrates it shows a marked preference for Leu-4-methylcoumaryl-7-amide (Leu-MCA) over Met-MCA, Arg-LCA and Lys-LCA. Cleaves the N-terminal amino acid of several peptides such as angiotensin-3, kisspeptin-10 and endokinin C.
Gene Name: | Laeverin |
Synonyms: | LVRN, Aminopeptidase Q, AP-Q, APQ, AQPEP, CHL2 antigen, Laeverin |
Target Sequences: | NM_173800 NP_776161.3 Q6Q4G3 |
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