Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
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LTBR is a member of the tumor necrosis factor receptor superfamily. The major ligands of this receptor include lymphotoxin alpha/beta and tumor necrosis factor ligand superfamily member 14. The encoded protein plays a role in signalling during the development of lymphoid and other organs, lipid metabolism, immune response, and programmed cell death. Activity of this receptor has also been linked to carcinogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed.
|Gene Name:||lymphotoxin beta receptor (TNFR superfamily, member 3)|
|Family/Subfamily:||TNF Receptor , not assigned-TNF Receptor|
|Synonyms:||LTBR, D12S370, CD18, LT-BETA-R, Lymphotoxin B receptor, Lymphotoxin-beta receptor, TNFR3, TNF-R-III, TNF-RIII, TNFCR, TNFRSF3, TNFR-III, TNFR-RP, TNFR2-RP|
|Target Sequences:||NM_002342 NP_002333.1 P36941|
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