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LRTOMT

leucine rich transmembrane and O-methyltransferase domain containing

This gene includes two transcript forms. The short form has one open reading frame (ORF), which encodes the leucine-rich repeats (LRR)-containing protein of unknown function. This protein is called LRTOMT1 or LRRC51. The long form has two alternative ORFs; the upstream ORF has the same translation start codon as used in the short form and the resulting transcript is a candidate for nonsense-mediated decay, and the downstream ORF encodes a different protein, which is a transmembrane catechol-O-methyltransferase and is called LRTOMT2, TOMT or COMT2. The COMT2 is essential for auditory and vestibular function. Defects in the COMT2 can cause nonsyndromic deafness. Alternatively spliced transcript variants from each transcript form have been found for this gene.

Gene Name: leucine rich transmembrane and O-methyltransferase domain containing
Synonyms: LRTOMT, Catechol O-methyltransferase 2, COMT2, DFNB63, Protein LRTOMT2, LRRC51, LRTOMT2, TOMT, LRTOMT1, Protein LRTOMT1
Target Sequences: H43229 NP_001138779.1 Q96E66

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Proteins (7)
Over-Expression Lysate (6)
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LRTOMT (7)
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Myc-DDK (Flag) (7)
Human (4)
293T Cells (3)
HEK 293 Cells (4)
LRTOMT Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
32 kDa
100 µg/$494
LRTOMT Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
18 kDa
100 µg/$494
LRTOMT Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
22 kDa
100 µg/$494
LRTOMT Protein - Purified recombinant protein LRTOMT was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
22 kDa
20 µg/$1,107
LRTOMT Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
32 kDa
20 µg/$150
LRTOMT Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
18 kDa
20 µg/$150
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293T Cells
Myc-DDK (Flag)
22 kDa
20 µg/$150
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).