LRP2 / Megalin

low density lipoprotein receptor-related protein 2

LRP2 / Megalin, low density lipoprotein-related protein 2 (LRP2) or megalin, is a multi-ligand endocytic receptor that is expressed in many different tissues but primarily in absorptive epithilial tissues such as the kidney. This glycoprotein has a large amino-terminal extracellular domain, a single transmembrane domain, and a short carboxy-terminal cytoplasmic tail. The extracellular ligand-binding-domains bind diverse macromolecules including albumin, apolipoproteins B and E, and lipoprotein lipase. The LRP2 protein is critical for the reuptake of numerous ligands, including lipoproteins, sterols, vitamin-binding proteins, and hormones. This protein also has a role in cell-signaling; extracellular ligands include parathyroid horomones and the morphogen sonic hedgehog while cytosolic ligands include MAP kinase scaffold proteins and JNK interacting proteins. Recycling of this membrane receptor is regulated by phosphorylation of its cytoplasmic domain. Mutations in this gene cause Donnai-Barrow syndrome (DBS) and facio-oculoacoustico-renal syndrome (FOAR).

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Products

Antibodies (33)

Type

Primary (33)

Target

LRP2 / Megalin (33)

Reactivity

Human (31)

Mouse (6)

Rat (5)

Application

IHC (13)

IHC-P (9)

WB (14)

ELISA (12)

Peptide-ELISA (1)

Host

rabbit (33)

Product Group

IHCPlus (2)

PathPlus Cancer (1)

Isotype

IgG (20)

Clonality

polyclonal pc (33)

Format

APC (1)

APC Conjugated (2)

Azide-free (1)

Biotin Conjugated (4)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (4)

HRP Conjugated (4)

PE Conjugated (2)

Preservative Free (2)

Unconjugated (15)

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Epitope

C-Terminus (8)

aa4035-4184 (8)

N-Terminus (1)

Publications

No (33)

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IHC-plus™ LRP2 / Megalin Antibody LS-B15411

(4.0) Rating

Antibody:

LRP2 / Megalin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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LRP2 / Megalin Antibody (C-Terminus) LS-C145128

Antibody:

LRP2 / Megalin Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$468

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LRP2 / Megalin Antibody (N-Terminus) LS-C47074

Antibody:

LRP2 / Megalin Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

0.1 mg/$379

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LRP2 / Megalin Antibody (aa4035-4184) LS-B15008

Antibody:

LRP2 / Megalin Rabbit anti-Human Polyclonal (aa4035-4184) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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LRP2 / Megalin Antibody LS-C804391

Antibody:

LRP2 / Megalin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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PathPlus™ LRP2 / Megalin Antibody LS-B16777

Cancer

(5.0) Rating

Antibody:

LRP2 / Megalin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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LRP2 / Megalin Antibody LS-C402355

Antibody:

LRP2 / Megalin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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LRP2 / Megalin Antibody (aa4035-4184, HRP) LS-C712241

Antibody:

LRP2 / Megalin Rabbit anti-Human Polyclonal (aa4035-4184) (HRP) Antibody

Reactivity:

Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$338; 200 µl/$393; 500 µl/$575; 1 ml/$702; 2 ml/$939; 5 ml/$1,593

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LRP2 / Megalin Antibody (aa4035-4184, Biotin) LS-C687693

Antibody:

LRP2 / Megalin Rabbit anti-Human Polyclonal (aa4035-4184) (Biotin) Antibody

Reactivity:

Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$596; 2 ml/$824; 5 ml/$1,348

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LRP2 / Megalin Antibody (aa4035-4184, FITC) LS-C694553

Antibody:

LRP2 / Megalin Rabbit anti-Human Polyclonal (aa4035-4184) (FITC) Antibody

Reactivity:

Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$348; 200 µl/$407; 500 µl/$605; 1 ml/$755; 2 ml/$993; 5 ml/$1,716

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LRP2 / Megalin Antibody (aa4035-4184, Cy3) LS-C703219

Antibody:

LRP2 / Megalin Rabbit anti-Human Polyclonal (aa4035-4184) (Cy3) Antibody

Reactivity:

Human

Applications:

WB

Format:

Cy3 Conjugated

Price:

100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451

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LRP2 / Megalin Antibody (aa4035-4184, APC) LS-C740915

Antibody:

LRP2 / Megalin Rabbit anti-Human Polyclonal (aa4035-4184) (APC) Antibody

Reactivity:

Human

Applications:

WB

Format:

APC Conjugated

Price:

100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451

• HRP
• Biotin
• FITC
• Cy3
• APC

• HRP
• Biotin
• FITC
• More...
  • Cy3
  • APC

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LRP2 / Megalin Antibody LS-C670613

Antibody:

LRP2 / Megalin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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LRP2 / Megalin Antibody LS-C751619

Antibody:

LRP2 / Megalin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$351

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LRP2 / Megalin Antibody LS-C670615

Antibody:

LRP2 / Megalin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

Select

LRP2 / Megalin Antibody (C-Terminus) LS-C330507

Antibody:

LRP2 / Megalin Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

200 µl/$734

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LRP2 / Megalin Antibody (C-Terminus, Biotin) LS-C278936

Antibody:

LRP2 / Megalin Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Biotin Conjugated

Price:

200 µl/$952

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LRP2 / Megalin Antibody (C-Terminus, FITC) LS-C278937

Antibody:

LRP2 / Megalin Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

FITC Conjugated

Price:

200 µl/$952

Select

LRP2 / Megalin Antibody (C-Terminus, PE) LS-C278939

Antibody:

LRP2 / Megalin Rabbit anti-Human Polyclonal (C-Terminus) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

PE Conjugated

Price:

200 µl/$952

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LRP2 / Megalin Antibody (C-Terminus, APC) LS-C278935

Antibody:

LRP2 / Megalin Rabbit anti-Human Polyclonal (C-Terminus) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

APC Conjugated

Price:

200 µl/$952

Select

LRP2 / Megalin Antibody (C-Terminus, Azide-free, HRP) LS-C278938

Antibody:

LRP2 / Megalin Rabbit anti-Human Polyclonal (C-Terminus) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• PE
• APC
• HRP, Azide-free

• Unconjugated
• Biotin
• FITC
• More...
  • PE
  • APC
  • HRP, Azide-free

Select

LRP2 / Megalin Antibody (Preservative Free) LS-C815153

Antibody:

LRP2 / Megalin Rabbit anti-Mouse Polyclonal (Preservative Free) Antibody

Reactivity:

Mouse

Applications:

IHC-P

Format:

Unconjugated, Preservative Free

Price:

100 µl/$412

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LRP2 / Megalin Antibody (C-Terminus) LS-C100401

Antibody:

LRP2 / Megalin Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Applications:

IHC-P

Format:

Unconjugated

Price:

400 µl/$393

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LRP2 / Megalin Antibody LS-C778041

Antibody:

LRP2 / Megalin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC-P

Format:

Unconjugated

Price:

100 µg/$357

Select

LRP2 / Megalin Antibody (Preservative Free) LS-C814920

Antibody:

LRP2 / Megalin Rabbit anti-Human Polyclonal (Preservative Free) Antibody

Reactivity:

Human

Applications:

IHC-P

Format:

Unconjugated, Preservative Free

Price:

100 µl/$412

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