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LPXN / Leupaxin

Leupaxin

Transcriptional coactivator for androgen receptor (AR) and serum response factor (SRF). Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negative regulator in integrin-mediated cell adhesion events. Suppresses the integrin-induced tyrosine phosphorylation of paxillin (PXN). May play a critical role as an adapter protein in the formation of the adhesion zone in osteoclasts. Negatively regulates B-cell antigen receptor (BCR) signaling.

Gene Name: Leupaxin
Synonyms: LPXN, LDLP, Leupaxin, LDPL
Target Sequences: NM_004811 NP_004802.1 O60711

Publications (1)

1
Protein tyrosine kinase 2b inhibition reverts niche-associated resistance to tyrosine kinase inhibitors in AML. Catana Allert, Alexander Waclawiczek , Sarah Miriam Naomi Zimmermann , Stefanie Göllner, Daniel Heid, Maike Janssen, Simon Renders, Christian Rohde, Marcus Bauer, Margarita Bruckmann, Rafael Zinz, Cornelius Pauli, Birgit Besenbeck, Claudia Wickenhauser, Andreas Trumpp, Jeroen Krijgsveld, Carsten Müller-Tidow, Maximilian Felix Blank. Leukemia. 2022 October;36:2418-2429. [Full Text Article] [PubMed:36056084] [PMC:PMC9522596] Related Antibodies: LS-C313296.

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Products
Antibodies (28)
Primary (28)
LPXN / Leupaxin (28)
Human (20)
Mouse (18)
Rat (3)
Monkey (1)
IHC (3)
IHC-P (1)
WB (23)
ELISA (12)
rabbit (27)
mouse (1)
IgG (14)
polyclonal pc (28)
APC (1)
APC Conjugated (2)
Azide-free (1)
Biotin Conjugated (4)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (2)
Unconjugated (10)
aa1-208 (8)
aa229-257 (7)
C-Terminus (4)
aa115-129 (1)
No (27)
Yes (1)
LPXN / Leupaxin Antibody - LPXN / Leupaxin antibody. IHC(P): Rat Spleen Tissue.
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LPXN / Leupaxin Rabbit anti-Human Polyclonal (aa115-129) Antibody
Mouse, Rat, Human, Monkey
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
LPXN / Leupaxin Antibody - LPXN Antibody western blot of mouse heart tissue lysates (35 ug/lane). The LPXN antibody detected the LPXN protein (arrow).
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LPXN / Leupaxin Rabbit anti-Human Polyclonal (aa229-257) Antibody
Mouse, Human
WB
Unconjugated
400 µl/$393
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LPXN / Leupaxin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
LPXN / Leupaxin Antibody - Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue  using LPXN Polyclonal Antibody at dilution of 1:60(×200)
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LPXN / Leupaxin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
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LPXN / Leupaxin Rabbit anti-Human Polyclonal (aa229-257) Antibody
Mouse, Human
ELISA, WB
Unconjugated
200 µl/$734
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LPXN / Leupaxin Rabbit anti-Human Polyclonal (aa229-257) (Biotin) Antibody
Mouse, Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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LPXN / Leupaxin Rabbit anti-Human Polyclonal (aa229-257) (FITC) Antibody
Mouse, Human
ELISA, WB
FITC Conjugated
200 µl/$952
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LPXN / Leupaxin Rabbit anti-Human Polyclonal (aa229-257) (PE) Antibody
Mouse, Human
ELISA, WB
PE Conjugated
200 µl/$952
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LPXN / Leupaxin Rabbit anti-Human Polyclonal (aa229-257) (APC) Antibody
Mouse, Human
ELISA, WB
APC Conjugated
200 µl/$952
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LPXN / Leupaxin Rabbit anti-Human Polyclonal (aa229-257) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
LPXN / Leupaxin Antibody - Immunohistochemistry of paraffin-embedded human lymph node tissue using LPXN Antibody at dilution of 1:100
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LPXN / Leupaxin Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
50 µg/$294; 100 µg/$360
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LPXN / Leupaxin Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
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LPXN / Leupaxin Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
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LPXN / Leupaxin Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
LPXN / Leupaxin Antibody - Western blot of LPXN / Leupaxin antibody.
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LPXN / Leupaxin Rabbit anti-Mouse Polyclonal (aa1-208) Antibody
Mouse
WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261
LPXN / Leupaxin Antibody - Western blot of LPXN / Leupaxin antibody.
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LPXN / Leupaxin Rabbit anti-Mouse Polyclonal (aa1-208) (HRP) Antibody
Mouse
WB
HRP Conjugated
100 µl/$342; 200 µl/$398; 500 µl/$585; 1 ml/$722; 2 ml/$959; 5 ml/$1,639
LPXN / Leupaxin Antibody - Western blot of LPXN / Leupaxin antibody.
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LPXN / Leupaxin Rabbit anti-Mouse Polyclonal (aa1-208) (Biotin) Antibody
Mouse
WB
Biotin Conjugated
100 µl/$321; 200 µl/$369; 500 µl/$527; 1 ml/$611; 2 ml/$842; 5 ml/$1,387
LPXN / Leupaxin Antibody - Western blot of LPXN / Leupaxin antibody.
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LPXN / Leupaxin Rabbit anti-Mouse Polyclonal (aa1-208) (FITC) Antibody
Mouse
WB
FITC Conjugated
100 µl/$352; 200 µl/$412; 500 µl/$622; 1 ml/$777; 2 ml/$1,014; 5 ml/$1,765
LPXN / Leupaxin Antibody - Western blot of LPXN / Leupaxin antibody.
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LPXN / Leupaxin Rabbit anti-Mouse Polyclonal (aa1-208) (PE) Antibody
Mouse
WB
PE Conjugated
100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521
LPXN / Leupaxin Antibody - Western blot of LPXN / Leupaxin antibody.
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LPXN / Leupaxin Rabbit anti-Mouse Polyclonal (aa1-208) (APC, Cy7) Antibody
Mouse
WB
APC, Cy7 Conjugated
100 µl/$513; 200 µl/$666; 500 µl/$1,175; 1 ml/$1,441; 2 ml/$2,017; 5 ml/$3,781
LPXN / Leupaxin Antibody - Western blot of LPXN / Leupaxin antibody.
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LPXN / Leupaxin Rabbit anti-Mouse Polyclonal (aa1-208) (Cy3) Antibody
Mouse
WB
Cy3 Conjugated
100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521
LPXN / Leupaxin Antibody - Western blot of LPXN / Leupaxin antibody.
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LPXN / Leupaxin Rabbit anti-Mouse Polyclonal (aa1-208) (APC) Antibody
Mouse
WB
APC Conjugated
100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521
LPXN / Leupaxin Antibody - Western blot analysis of extracts of various cells.
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LPXN / Leupaxin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
LPXN / Leupaxin Antibody - Western blot of LPXN Antibody with human Jurkat Whole Cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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LPXN / Leupaxin Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
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LPXN / Leupaxin Mouse anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µg/$705
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).