LPIN1 / Lipin 1

lipin 1

LPIN1 / Lipin 1 is a magnesium-ion-dependent phosphatidic acid phosphohydrolase enzyme that catalyzes the penultimate step in triglyceride synthesis including the dephosphorylation of phosphatidic acid to yield diacylglycerol. Expression of this gene is required for adipocyte differentiation and it also functions as a nuclear transcriptional coactivator with some peroxisome proliferator-activated receptors to modulate expression of other genes involved in lipid metabolism. Mutations in this gene are associated with metabolic syndrome, type 2 diabetes, and autosomal recessive acute recurrent myoglobinuria (ARARM). This gene is also a candidate for several human lipodystrophy syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their full-length structures have not been determined.

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Products

Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

LPIN1 / Lipin 1 (5)

Publications

No (5)

Tag

GST (1)

GST, N-terminus (1)

Myc-DDK (Flag) (3)

Species

Human (4)

Source

293T Cells (1)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (1)

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Human LPIN1 / Lipin 1 Protein (Recombinant GST) (Full Length) - LS-G32752

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

123.64 kDa

Price:

2 µg/$439

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Human LPIN1 / Lipin 1 Protein (Recombinant GST, N-terminus) (aa792-890) - LS-G61933

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human LPIN1 / Lipin 1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G65979

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

98.5 kDa

Price:

20 µg/$1,107

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Human LPIN1 / Lipin 1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G76689

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

98.5 kDa

Price:

20 µg/$150

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LPIN1 / Lipin 1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G106615

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

98.5 kDa

Price:

100 µg/$494

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