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LPAR3 / LPA3 / EDG7

lysophosphatidic acid receptor 3

Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. May play a role in the development of ovarian cancer. Seems to be coupled to the G(i)/G(o) and G(q) families of heteromeric G proteins.

Gene Name: lysophosphatidic acid receptor 3
Family/Subfamily: GPCR , Lysophospholipid/Lysosphingolipid
Synonyms: LPAR3, EDG7, Edg-7, LPA receptor 3, HOFNH30, LPA3, RP4-678I3, LP-A3, LPA receptor EDG7, LPA-3
Target Sequences: NM_012152 NP_036284.1 Q9UBY5

Publications (3)

1
Reduced expression of biomarkers associated with the implantation window in women with endometriosis. Qingxiang Wei, J. Benjamin St. Clair, Teresa Fu, Pamela Stratton, Lynnette K. Nieman. Fertility and sterility. 2009 91:1686-91. (IHC-P; Human) [Full Text Article] [PubMed:18672236] [PMC:PMC2697117] Related Antibodies: LS-A1014.
2
Elevated plasma levels of lysophosphatidic acid and aberrant expression of lysophosphatidic acid receptors in adenomyosis. Yang B, Wang L, Wan X, Li Y, Yu X, Qin Y, Luo Y, Wang F, Huang O. BMC women's health. 2017 November;17:118. (Human) [Full Text Article] [PubMed:29178922] [PMC:PMC5702234] Related Antibodies: LS-A1014.
3
Lysophosphatidic acid acts on LPA1 receptor to increase H2O2 during flow-induced dilation in human adipose arterioles. Dawid S Chabowski, Andrew O Kadlec. Karima Ait-Aissa, Joseph C Hockenberry, Paul J Pearson, Andreas M Beyer, David D Gutterman. 2018 August;175:4266-4280. [Full Text Article] [PubMed:30153326] [PMC:PMC6193883 ] Related Antibodies: LS-A1014.

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).