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LOXL3

lysyl oxidase-like 3

LOXL3 is a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. Alternatively spliced transcript variants of this gene have been reported but their full-length nature has not been determined.

Gene Name: lysyl oxidase-like 3
Synonyms: LOXL3, Lysyl oxidase homolog 3, LOXL, Lysyl oxidase-like 3, Lysyl oxidase-like protein 3
Target Sequences: NM_032603 NP_115992.1 P58215

Publications (1)

1
Comparative analysis of lysyl oxidase (like) family members in pulmonary fibrosis. Aumiller V, Strobel B, Romeike M, Schuler M, Stierstorfer BE, Kreuz S. Scientific reports. 2017 March;7:149. (Human) [Full Text Article] [PubMed:28273952] [PMC:PMC5428068] Related Antibodies: LS-C165846.

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LOXL3 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
LOXL3 ELISA Kit
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Custom
96-Well Strip Plate
Human
Colorimetric - 450nm (TMB)
1 Plate/$783
LOXL3 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.47 - 30 pmol/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
LOXL3 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$834
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).