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LNPEP
leucyl/cystinyl aminopeptidase
Release of an N-terminal amino acid, cleaves before cysteine, leucine as well as other amino acids. Degrades peptide hormones such as oxytocin, vasopressin and angiotensin III, and plays a role in maintaining homeostasis during pregnancy. May be involved in the inactivation of neuronal peptides in the brain. Cleaves Met-enkephalin and dynorphin. Binds angiotensin IV and may be the angiotensin IV receptor in the brain.
| Gene Name: | leucyl/cystinyl aminopeptidase |
| Family/Subfamily: | Exopeptidase , Metallopeptidase M1 |
| Synonyms: | LNPEP, Angiotensin IV receptor, CAP, Cystinyl aminopeptidase, Leucyl/cystinyl aminopeptidase, P-LAP, PLAP, IRAP, Leucyl-cystinyl aminopeptidase, Vasopressinase, Otase, AT (4) receptor, Oxytocinase, Oxytocinase variant 2 |
| Target Sequences: | NM_005575 NP_005566.2 Q9UIQ6 |
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