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LMNB1 / Lamin B1

lamin B1

In animal cells, there are A- and B-type lamins, which differ in their length and isoelectric point (pI). Human cells have three differentially regulated genes. B-type lamins are present in every cell. B type lamins, B1 and B2, are expressed from the LMNB1 and LMNB2 genes on 5q23 and 19q13, respectively. A-type lamins are expressed only following gastrulation. Lamin A and C are the most common A-type lamins and are splice variants of the LMNA gene found at 1q21.

Gene Name: lamin B1
Synonyms: LMNB1, ADLD, Lamin B1, Lamin-B1, LMN, LMNB, LMN2
Target Sequences: NM_005573 NP_005564.1 P20700

Publications (2)

1
Effect of estradiol on high glucose-induced osteoblast injury. Li G, Jiang X, Liu L, Liu X, Liu H, Zhang Z. Molecular medicine reports. 2019 October;20:3019-3026. [Full Text Article] [PubMed:31432111] [PMC:PMC6755179] Related Antibodies: LS-B6062.
2
Multisystem proteinopathy due to a homozygous p.Arg159His VCP mutation: A tale of the unexpected. Willem De Ridder, Abdelkrim Azmi, Christoph S Clemen, Ludwig Eichinger, Andreas Hofmann, Rolf Schröder, Katherine Johnson, Ana Töpf, Volker Straub, Peter De Jonghe, Stuart Maudsley, Jan L De Bleecker, Jonathan Baets. Neurology. 2020 February;94:e785-e796. [Full Text Article] [PubMed:31848255] Related Antibodies: LS-B11184.

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Proteins (7)
Over-Expression Lysate (2)
Recombinant (5)
LMNB1 / Lamin B1 (7)
No (7)
GST (1)
GST, N-terminus (1)
His, N-terminus (1)
His-T7 (1)
Myc-DDK (Flag) (3)
Human (5)
Rat (1)
293T Cells (1)
E. coli (2)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (1)
LMNB1 / Lamin B1 Protein - Purified recombinant protein LMNB1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
66.2 kDa
20 µg/$1,107
LMNB1 / Lamin B1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
LMNB1 / Lamin B1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
66.2 kDa
100 µg/$494
LMNB1 / Lamin B1 Protein - Recombinant Rat Lamin B1 Protein (His Tag)-Elabscience
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E. coli
His, N-terminus
22.1 kDa
20 µg/$270; 100 µg/$390
LMNB1 / Lamin B1 Protein - 12.5% SDS-PAGE of human LMNB1 stained with Coomassie Blue
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Wheat Germ Extract
GST
92.8 kDa
10 µg/$479; 25 µg/$670
LMNB1 / Lamin B1 Protein - Recombinant  Lamin B1 By SDS-PAGE
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E. coli
His-T7
24.2 kDa
10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
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293T Cells
Myc-DDK (Flag)
66.2 kDa
20 µg/$150
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).