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LMCD1

LIM and cysteine-rich domains 1

Transcriptional cofactor that restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes. Represses GATA6-mediated trans activation of lung- and cardiac tissue-specific promoters. Inhibits DNA-binding by GATA4 and GATA1 to the cTNC promoter (By similarity). Plays a critical role in the development of cardiac hypertrophy via activation of calcineurin/nuclear factor of activated T-cells signaling pathway.

Gene Name: LIM and cysteine-rich domains 1
Synonyms: LMCD1, Dyxin
Target Sequences: NM_014583 NP_055398.1 Q9NZU5

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Products
Antibodies (15)
Primary (15)
LMCD1 (15)
Human (15)
Mouse (3)
Rat (1)
IHC (5)
IHC-P (3)
WB (9)
Flo (6)
ELISA (3)
IF (6)
Peptide-ELISA (1)
rabbit (8)
mouse (7)
IgG (8)
IgG1 (4)
IgG2b (2)
monoclonal mc (6)
polyclonal pc (9)
OTI1H5 (2)
OTI2F12 (2)
OTI2G5 (2)
Biotin Conjugated (1)
Carrier-free (3)
FITC Conjugated (1)
HRP Conjugated (1)
Unconjugated (12)
aa316-350 (1)
No (15)
LMCD1 Antibody - Western blot of lysates from human skeletal muscle, mouse lung, rat lung tissue lysate (from left to right), using LMCD1 antibody diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L (HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20 ug per lane.
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LMCD1 Rabbit anti-Human Polyclonal (aa316-350) Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
400 µl/$393
LMCD1 Antibody - IHC of paraffin-embedded Human lymphoma tissue using anti-LMCD1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
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LMCD1 Mouse anti-Human Monoclonal (OTI1H5) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
LMCD1 Antibody - IHC of paraffin-embedded Human lymphoma tissue using anti-LMCD1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
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LMCD1 Mouse anti-Human Monoclonal (Carrier-free) (OTI1H5) Antibody
Human
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
LMCD1 Antibody - Immunohistochemistry image at a dilution of 1:300 and staining in paraffin-embedded human lung tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0) . Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4 °C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
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LMCD1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
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LMCD1 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
HRP Conjugated
50 µg/$294; 100 µg/$360
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LMCD1 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
Biotin Conjugated
50 µg/$294; 100 µg/$360
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LMCD1 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
FITC Conjugated
50 µg/$294; 100 µg/$360
LMCD1 Antibody - Anti-LMCD1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY LMCD1.
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LMCD1 Mouse anti-Human Monoclonal (OTI2G5) Antibody
Human
Flo, IF, WB
Unconjugated
100 µl/$434
LMCD1 Antibody - Anti-LMCD1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY LMCD1.
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LMCD1 Mouse anti-Human Monoclonal (Carrier-free) (OTI2G5) Antibody
Human
Flo, IF, WB
Unconjugated, Carrier-free
100 µg/$511
LMCD1 Antibody - Immunohistochemistry of paraffin-embedded Human tonsil tissue  using LMCD1 Polyclonal Antibody at dilution of 1:100(×200)
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LMCD1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
LMCD1 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY LMCD1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-LMCD1.
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LMCD1 Mouse anti-Human Monoclonal (OTI2F12) Antibody
Human
Flo, WB
Unconjugated
100 µl/$434
LMCD1 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY LMCD1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-LMCD1.
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LMCD1 Mouse anti-Human Monoclonal (Carrier-free) (OTI2F12) Antibody
Human
Flo, WB
Unconjugated, Carrier-free
100 µg/$511
LMCD1 Antibody - Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue  using LMCD1 Polyclonal Antibody at dilution of 1:80(×200)
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LMCD1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
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LMCD1 Mouse anti-Human Polyclonal Antibody
Human
IF, WB
Unconjugated
50 µg/$705
LMCD1 Antibody - Immunochemical staining of human LMCD1 in human kidney with rabbit polyclonal antibody at 1:500 dilution, formalin-fixed paraffin embedded sections.
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LMCD1 Rabbit anti-Human Polyclonal Antibody
Human
IHC-P
Unconjugated
100 µl/$412
Viewing 1-15 of 15 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).