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LLGL1 / HUGL
lethal giant larvae homolog 1 (Drosophila)
Cortical cytoskeleton protein found in a complex involved in maintaining cell polarity and epithelial integrity. Involved in the regulation of mitotic spindle orientation, proliferation, differentiation and tissue organization of neuroepithelial cells. Involved in axonogenesis through RAB10 activation thereby regulating vesicular membrane trafficking toward the axonal plasma membrane.
| Gene Name: | lethal giant larvae homolog 1 (Drosophila) |
| Synonyms: | LLGL1, HUGL1, HUGL, LLGL, HUGL-1 |
| Target Sequences: | NM_004140 NP_004131.3 Q15334 |
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