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LIPG / Endothelial Lipase

lipase, endothelial

LIPG (endothelial lipase) has substantial phospholipase activity and may be involved in lipoprotein metabolism and vascular biology. This protein is designated a member of the TG lipase family by its sequence and characteristic lid region which provides substrate specificity for enzymes of the TG lipase family.

Gene Name:	lipase, endothelial
Synonyms:	LIPG, EDL, EL, Lipoprotein lipase H, Lipase, endothelial, PRO719, Endothelial lipase
Target Sequences:	NM_006033 NP_006024.1 Q9Y5X9

Publications (4)

Scavenger receptor BI-mediated selective uptake is required for the remodeling of high density lipoprotein by endothelial lipase. Nijstad N, Wiersma H, Gautier T, van der Giet M, Maugeais C, Tietge UJ. The Journal of biological chemistry. 2009 284:6093-100. [PubMed:19136670]

Hepatic SR-BI, not endothelial lipase, expression determines biliary cholesterol secretion in mice. Wiersma H, Gatti A, Nijstad N, Kuipers F, Tietge UJ. Journal of lipid research. 2009 50:1571-80. [PubMed:19252221] [PMC:PMC2724056]

Endothelial Lipase Plasma Levels are Increased in Patients With Significant Carotid Artery Stenosis and History of Neurological Impairment. Riederer M, Trbui M, Degoricija V, Frank S. Journal of clinical medicine research. 2012 4:49-51. (ELISA; Human) [PubMed:22383927] [PMC:PMC3279501]

The Hepatic Microenvironment Uniquely Protects Leukemia Cells through Induction of Growth and Survival Pathways Mediated by LIPG. Haobin Ye, Mohammad Minhajuddin, Anna Krug, Shanshan Pei, Chih-Hsing Chou, Rachel Culp-Hill, Jessica Ponder, Erik De Bloois, Björn Schniedewind, Maria L Amaya, Anagha Inguva, Brett M Stevens, Daniel A Pollyea, Uwe Christians, H Leighton Grimes, Angelo D'Alessandro, Craig T Jordan. Cancer discovery. 2021 February;11:500-519. [Full Text Article] [PubMed:33028621] [PMC:PMC7858222] Related Antibodies: LS-C348949.

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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