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LIPE / HSL

lipase, hormone-sensitive

In adipose tissue and heart, it primarily hydrolyzes stored triglycerides to free fatty acids, while in steroidogenic tissues, it principally converts cholesteryl esters to free cholesterol for steroid hormone production.

Gene Name: lipase, hormone-sensitive
Synonyms: LIPE, Hormone-sensitive lipase, LHS, HSL, Lipase, hormone-sensitive
Target Sequences: NM_005357 NP_005348.2 Q05469

Publications (3)

1
Detection of hormone-sensitive lipase in various tissues. I. Expression of an HSL/bacterial fusion protein and generation of anti-HSL antibodies. Kraemer FB, Patel S, Saedi MS, Sztalryd C. Journal of lipid research. 1993 34:663-71. (WB; Rat) [PubMed:8496671]
2
Shc proteins influence the activities of enzymes involved in fatty acid oxidation and ketogenesis. Hagopian K, Tomilov AA, Tomilova N, Kim K, Taylor SL, Lam AK, Cortopassi GA, McDonald RB, Ramsey JJ. Metabolism: clinical and experimental. 2012 61:1703-13. (WB; Mouse) [PubMed:22683097] [PMC:PMC3442136]
3
Activation of Cx43 Hemichannels Induces the Generation of Ca2+ Oscillations in White Adipocytes and Stimulates Lipolysis. Egor A Turovsky, Elena G Varlamova, Maria V Turovskaya. International journal of molecular sciences. 2021 July;22: [Full Text Article] [PubMed:34360859] [PMC:PMC8347185] Related Antibodies: LS-C417602.

☰ Filters
Products
Antibodies (34)
Primary (34)
LIPE / HSL (34)
Human (32)
Mouse (23)
Rat (20)
Monkey (2)
Pig (1)
IHC (26)
IHC-P (10)
WB (29)
Flo (1)
ELISA (14)
IF (6)
IP (2)
Peptide-ELISA (7)
rabbit (33)
chicken (1)
Product Group
IHCPlus (2)
IgG (22)
IgY (1)
polyclonal pc (34)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
Unconjugated (31)
pSer552 (5)
490-570 aa (3)
pSer855/554 (2)
C-Terminus (1)
Internal (1)
Pro548 (1)
aa518-567 (1)
aa520-569 (1)
aa699-908 (1)
aa822-849 (1)
p552 (1)
p554 (1)
pSer855 (1)
pSer855,pSer554 (1)
pSer855/Ser554 (1)
No (33)
Yes (1)
Select
LIPE / HSL Rabbit anti-Human Polyclonal Antibody
Human
IF, IP, WB
Unconjugated
100 µl/$688
LIPE / HSL Antibody - Western blot of HSL expression in Jurkat whole cell lysates,The lane on the left is treated with the antigen-specific peptide.
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LIPE / HSL Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µg/$305; 100 µg/$357
LIPE / HSL Antibody - Immunohistochemistry analysis of paraffin-embedded human tonsil tissue, using HSL Antibody. The picture on the right is blocked with the synthesized peptide.
Select
LIPE / HSL Rabbit anti-Human Polyclonal (aa518-567) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
LIPE / HSL Antibody - Western blot analysis of HSL (pS855) expression in Human muscle (A) whole cell lysates.
Select
LIPE / HSL Rabbit anti-Human Polyclonal (pSer855) Antibody
Pig, Human
WB
Unconjugated
100 µl/$315
Select
LIPE / HSL Chicken anti-Mouse Polyclonal Antibody
Mouse
ELISA, WB
Unconjugated
500 µg/$763
LIPE / HSL Antibody - 1:100 staining human prostate tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
Select
LIPE / HSL Rabbit anti-Human Polyclonal (pSer855,pSer554) Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
LIPE / HSL Antibody - 1:100 staining human prostate tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
Select
LIPE / HSL Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
LIPE / HSL Antibody - 1:100 staining human brain tissue by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
Select
LIPE / HSL Rabbit anti-Human Polyclonal (pSer552) Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
LIPE / HSL Antibody - Formalin-fixed and paraffin-embedded human testis tissue reacted with LIPE Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Select
LIPE / HSL Rabbit anti-Human Polyclonal (aa822-849) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
LIPE / HSL Antibody - Immunohistochemistry of paraffin-embedded human glioma cancer using LIPE Antibody at dilution of 1:100
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LIPE / HSL Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC
Unconjugated
50 µg/$294; 100 µg/$360
LIPE / HSL Antibody - Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using HSL (Phospho-Ser552) Antibody. The picture on the right is blocked with the phospho peptide.
Select
LIPE / HSL Rabbit anti-Human Polyclonal (pSer552) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
LIPE / HSL Antibody - Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using HSL Antibody. The picture on the right is blocked with the synthesized peptide.
Select
LIPE / HSL Rabbit anti-Human Polyclonal (aa520-569) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
LIPE / HSL Antibody - Immunohistochemistry analysis of paraffin-embedded human colon carcinoma, using HSL (Phospho-Ser855/554) Antibody. The picture on the right is blocked with the phospho peptide.
Select
LIPE / HSL Rabbit anti-Human Polyclonal (pSer855/Ser554) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
LIPE / HSL Antibody - Immunohistochemical analysis of HSL staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Select
LIPE / HSL Rabbit anti-Human Polyclonal (Internal) Antibody
Human, Monkey
IHC, IHC-P, IP, WB
Unconjugated
100 µl/$299
LIPE / HSL Antibody - Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE), at a dilution of 1:100.
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LIPE / HSL Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
60 µl/$460
LIPE / HSL Antibody - Western blot of Phospho-HSL (S552) antibody
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LIPE / HSL Rabbit anti-Human Polyclonal (490-570 aa) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
LIPE / HSL Antibody - Western blot of Phospho-HSL (S855) antibody
Select
LIPE / HSL Rabbit anti-Human Polyclonal (490-570 aa) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
LIPE / HSL Antibody - Western blot of HSL antibody
Select
LIPE / HSL Rabbit anti-Human Polyclonal (490-570 aa) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
LIPE / HSL Antibody - P-peptide - + Immunohistochemical analysis of paraffin-embedded human colon carcinoma tissue using HSL (Phospho-Ser855/554) antibody.
Select
LIPE / HSL Rabbit anti-Human Polyclonal (pSer855/554) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
LIPE / HSL Antibody - Peptide - + Immunohistochemistry analysis of paraffin-embedded human tonsil tissue using HSL (Ab-552) antibody.
Select
LIPE / HSL Rabbit anti-Human Polyclonal (p552) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
LIPE / HSL Antibody - P-peptide - + Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using HSL (Phospho-Ser552) antibody.
Select
LIPE / HSL Rabbit anti-Human Polyclonal (pSer552) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
LIPE / HSL Antibody - Peptide - + Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using HSL (Ab-554) antibody.
Select
LIPE / HSL Rabbit anti-Human Polyclonal (p554) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
Select
LIPE / HSL Rabbit anti-Mouse Polyclonal (C-Terminus) Antibody
Mouse
IHC, WB
Unconjugated
100 µl/$440; 200 µl/$468
LIPE / HSL Antibody - IHC of HSL pAb in paraffin-embedded human breast carcinoma tissue.
Select
LIPE / HSL Rabbit anti-Human Polyclonal (Pro548) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$321; 100 µl/$403
LIPE / HSL Antibody - Immunohistochemical analysis of HSL (pS552) staining in human lymph node formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Select
LIPE / HSL Rabbit anti-Human Polyclonal (pSer552) Antibody
Human, Monkey
IHC, IHC-P, WB
Unconjugated
100 µl/$315
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).