LIMD1

LIM domains containing 1

Adapter or scaffold protein which participates in the assembly of numerous protein complexes and is involved in several cellular processes such as cell fate determination, cytoskeletal organization, repression of gene transcription, cell-cell adhesion, cell differentiation, proliferation and migration. Positively regulates microRNA (miRNA)-mediated gene silencing and is essential for P-body formation and integrity. Acts as a hypoxic regulator by bridging an association between the prolyl hydroxylases and VHL enabling efficient degradation of HIF1A. Acts as a transcriptional corepressor for SNAI1- and SNAI2/SLUG-dependent repression of E-cadherin transcription. Negatively regulates the Hippo signaling pathway and antagonizes phosphorylation of YAP1. Inhibits E2F-mediated transcription, and suppresses the expression of the majority of genes with E2F1-responsive elements. Regulates osteoblast development, function, differentiation and stress osteoclastogenesis. Enhances the ability of TRAF6 to activate adapter protein complex 1 (AP-1) and negatively regulates the canonical Wnt receptor signaling pathway in osteoblasts. May act as a tumor suppressor by inhibiting cell proliferation.

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Products

Antibodies (15)

Type

Primary (15)

Target

LIMD1 (15)

Reactivity

Human (15)

Mouse (10)

Rat (3)

Bovine (3)

Chimpanzee (3)

Gibbon (3)

Guinea pig (3)

Hamster (3)

Monkey (3)

Pig (3)

Rabbit (3)

Zebrafish (3)

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Application

IHC (13)

IHC-P (6)

WB (14)

ELISA (8)

IP (2)

Host

rabbit (14)

mouse (1)

Product Group

IHCPlus (2)

Isotype

IgG (12)

IgG2b,k (1)

Clonality

monoclonal mc (1)

polyclonal pc (14)

Clone

2G5 (1)

Format

APC Conjugated (1)

Azide-free (1)

Biotin Conjugated (2)

FITC Conjugated (2)

HRP Conjugated (2)

PE Conjugated (1)

Unconjugated (7)

Epitope

aa438-467 (7)

N-Terminus (4)

aa1-50 (1)

aa395-593 (1)

aa50-100 (1)

Publications

No (15)

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LIMD1 Antibody (N-Terminus) LS-B4017

Antibody:

LIMD1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$485

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LIMD1 Antibody (N-Terminus, HRP) LS-C453908

Antibody:

LIMD1 Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody

Reactivity:

Zebrafish, Rat, Hamster, Rabbit, Mouse, Guinea pig, Bovine, Pig, Gibbon, Human, Monkey, Chimpanzee

Applications:

IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

100 µl/$469

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LIMD1 Antibody (N-Terminus, Biotin) LS-C453906

Antibody:

LIMD1 Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody

Reactivity:

Zebrafish, Rat, Hamster, Rabbit, Mouse, Guinea pig, Bovine, Pig, Gibbon, Human, Monkey, Chimpanzee

Applications:

IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

100 µl/$469

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LIMD1 Antibody (N-Terminus, FITC) LS-C453907

Antibody:

LIMD1 Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody

Reactivity:

Zebrafish, Rat, Hamster, Rabbit, Mouse, Guinea pig, Bovine, Pig, Gibbon, Human, Monkey, Chimpanzee

Applications:

IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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IHC-plus™ LIMD1 Antibody (aa438-467) LS-B9619

(4.0) Rating

Antibody:

LIMD1 Rabbit anti-Human Polyclonal (aa438-467) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

200 µl/$460

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LIMD1 Antibody (clone 2G5) LS-C133991

Antibody:

LIMD1 Mouse anti-Human Monoclonal (2G5) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$423

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LIMD1 Antibody (aa395-593) LS-C179147

Antibody:

LIMD1 Rabbit anti-Human Polyclonal (aa395-593) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µl/$332

Select

LIMD1 Antibody (aa438-467) LS-C322658

Antibody:

LIMD1 Rabbit anti-Human Polyclonal (aa438-467) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

LIMD1 Antibody (aa438-467, Biotin) LS-C237130

Antibody:

LIMD1 Rabbit anti-Human Polyclonal (aa438-467) (Biotin) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

LIMD1 Antibody (aa438-467, FITC) LS-C237129

Antibody:

LIMD1 Rabbit anti-Human Polyclonal (aa438-467) (FITC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

LIMD1 Antibody (aa438-467, Azide-free, HRP) LS-C248709

Antibody:

LIMD1 Rabbit anti-Human Polyclonal (aa438-467) (Azide-free) (HRP) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

LIMD1 Antibody (aa438-467, APC) LS-C237128

Antibody:

LIMD1 Rabbit anti-Human Polyclonal (aa438-467) (APC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

LIMD1 Antibody (aa438-467, PE) LS-C237131

Antibody:

LIMD1 Rabbit anti-Human Polyclonal (aa438-467) (PE) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• HRP, Azide-free
• APC
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • HRP, Azide-free
  • APC
  • PE

Select

LIMD1 Antibody (aa50-100) LS-C289880

Antibody:

LIMD1 Rabbit anti-Human Polyclonal (aa50-100) Antibody

Reactivity:

Human

Applications:

IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

Select

LIMD1 Antibody (aa1-50) LS-C289878

Antibody:

LIMD1 Rabbit anti-Human Polyclonal (aa1-50) Antibody

Reactivity:

Human

Applications:

IP

Format:

Unconjugated

Price:

10 µg/$295; 100 µl/$514

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