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2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
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Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
Telephone Numbers
Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565
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Additional Contact Details
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LILRB5 / LIR8
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5
LILRB5 / LIR8 is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). Several other LIR subfamily B receptors are expressed on immune cells where they bind to MHC class I molecules on antigen-presenting cells and inhibit stimulation of an immune response. Multiple transcript variants encoding different isoforms have been found for this gene.
| Gene Name: | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5 |
| Family/Subfamily: | Immunoglobulin , not assigned-Immunoglobulin |
| Synonyms: | LILRB5, CD85c antigen, LIR-8, LIR8, CD85C |
| Target Sequences: | NM_006840 NP_006831.1 O75023 |
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