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LILRA2 / CD85h / ILT1

leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2

LILRA2 / ILT1 is a member of a family of immunoreceptors that are expressed predominantly on monocytes and B cells, and at lower levels on dendritic cells and natural killer cells. The encoded protein is an activating receptor that inhibits dendritic cell differentiation and antigen presentation and suppresses innate immune response. Alternatively spliced transcript variants encoding different isoforms have been found. This gene is located in a cluster of related genes on chromosome 19 and there is a pseudogene for this gene on chromosome 3.

Gene Name: leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
Synonyms: LILRA2, CD85H, CD85h antigen, ILT-1, ILT1, LIR-7, LIR7
Target Sequences: NP_006857.2

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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).