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LGALS9 / Galectin 9

lectin, galactoside-binding, soluble, 9

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS9 is an S-type lectin. This galectin is strongly overexpressed in Hodgkin&#039s disease tissue and it might participate in the interaction between the H&RS cells with their surrounding cells and might thus play a role in the pathogenesis of this disease and/or its consistently associated immunodeficiency. The protein has N- and C- terminal carbohydrate-binding domains connected by a link peptide. Two isoforms (long and short) exist.

Gene Name: lectin, galactoside-binding, soluble, 9
Synonyms: LGALS9, Gal-9, HUAT, Galectin 9, Galectin-9, LGALS9A, Tumor antigen HOM-HD-21, Ecalectin
Target Sequences: NM_009587 NP_033665.1 O00182

Publications (3)

1
Elevated cerebrospinal fluid Galectin-9 is associated with central nervous system immune activation and poor cognitive performance in older HIV-infected individuals. Thomas A Premeaux, Michelle L D'Antoni, Mohamed Abdel-Mohsen, Satish K Pillai, Kalpana J Kallianpur, Beau K Nakamoto, Melissa Agsalda-Garcia, Bruce Shiramizu, Cecilia M Shikuma, Magnus Gisslén, Richard W Price, Victor Valcour, Lishomwa C Ndhlovu. Journal of neurovirology. 2019 April;25:150-161. [Full Text Article] [PubMed:30478799] [PMC:PMC6506351] Related Antibodies: LS-B12783.
2
Targeting the C-terminus of galectin-9 induces mesothelioma apoptosis and M2 macrophage depletion. Pietro Bertino, Thomas A Premeaux, Tsuyoshi Fujita, Brien K Haun, Michael P Marciel, Fukun W Hoffmann, Alan Garcia, Haining Yiang, Sandra Pastorino, Michele Carbone, Toshiro Niki, John Berestecky, Peter R Hoffmann, Lishomwa C Ndhlovu. Oncoimmunology. 2019 Apr;8:1601482. [Full Text Article] [PubMed:31413910] [PMC:PMC6682368] Related Antibodies: LS-B6275.
3
The CD155/TIGIT axis promotes and maintains immune evasion in neoantigen-expressing pancreatic cancer. William A Freed-Pastor, Laurens J Lambert, Zackery A Ely, Nimisha B Pattada, Arjun Bhutkar, George Eng, Kim L Mercer, Ana P Garcia, Lin Lin, William M Rideout rd, William L Hwang, Jason M Schenkel, Alex M Jaeger, Roderick T Bronson, Peter M K Westcott, Tyler D Hether, Prajan Divakar, Jason W Reeves, Vikram Deshpande, Toni Delorey, Devan Phillips, Omer H Yilmaz, Aviv Regev, Tyler Jacks. Cancer cell. 2021 October;39:1342-1360.e14. [Full Text Article] [PubMed:34358448] [PMC:PMC8511341] Related Antibodies: LS-B6275.

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Antibodies (98)
Primary (98)
LGALS9 / Galectin 9 (98)
Human (57)
Mouse (35)
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Cow (8)
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IP (1)
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rabbit (80)
mouse (18)
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monoclonal mc (18)
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recombinant monoclonal rmc (1)
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30-110 aa, Internal (1)
Gly80 (1)
Internal (1)
aa1-240 (1)
aa1-323 (1)
aa51-100 (1)
No (96)
Yes (2)
LGALS9 / Galectin 9 Antibody - Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
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LGALS9 / Galectin 9 Mouse anti-Human Monoclonal (1G3) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
LGALS9 / Galectin 9 Antibody - Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-LGALS9 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min,
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LGALS9 / Galectin 9 Mouse anti-Human Monoclonal (Carrier-free) (OTI21B5) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
LGALS9 / Galectin 9 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY LGALS9. (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates. (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-LGALS9.
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LGALS9 / Galectin 9 Mouse anti-Human Monoclonal (Carrier-free) (OTI1G3) Antibody
Human
WB
Unconjugated, Carrier-free
100 µg/$511
LGALS9 / Galectin 9 Antibody - Western blot of Galectin-9 antibody
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LGALS9 / Galectin 9 Rabbit anti-Human Polyclonal (30-110 aa, Internal) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
LGALS9 / Galectin 9 Antibody - Immunohistochemical staining of paraffin-embedded Carcinoma of Human pancreas tissue using anti-LGALS9 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0) Dilution: 1:150
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LGALS9 / Galectin 9 Mouse anti-Human Monoclonal (Carrier-free) (OTI19F7) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
LGALS9 / Galectin 9 Antibody - Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-LGALS9 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min,
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LGALS9 / Galectin 9 Mouse anti-Human Monoclonal (Carrier-free) (OTI2A4) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
LGALS9 / Galectin 9 Antibody - Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-LGALS9 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min,
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LGALS9 / Galectin 9 Mouse anti-Human Monoclonal (Carrier-free) (OTI19H8) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
LGALS9 / Galectin 9 Antibody - Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-LGALS9 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min,
Select
LGALS9 / Galectin 9 Mouse anti-Human Monoclonal (Carrier-free) (OTI8B11) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
LGALS9 / Galectin 9 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY LGALS9. (Right lane) cDNA for 48 hrs and lysed
Select
LGALS9 / Galectin 9 Mouse anti-Human Monoclonal (OTI16B4) Antibody
Human
WB
Unconjugated
100 µl/$434
LGALS9 / Galectin 9 Antibody - Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
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LGALS9 / Galectin 9 Mouse anti-Human Monoclonal (2A4) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
LGALS9 / Galectin 9 Antibody - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
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LGALS9 / Galectin 9 Mouse anti-Human Monoclonal (19H8) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
LGALS9 / Galectin 9 Antibody - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
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LGALS9 / Galectin 9 Mouse anti-Human Monoclonal (21B5) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
LGALS9 / Galectin 9 Antibody - Immunohistochemical analysis of Galectin 9 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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LGALS9 / Galectin 9 Rabbit anti-Human Polyclonal (Internal) Antibody
Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$299
LGALS9 / Galectin 9 Antibody - Fetal muscle lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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LGALS9 / Galectin 9 Rabbit anti-Human Polyclonal (aa218-267) Antibody
Human
WB
Unconjugated
100 µl/$424
LGALS9 / Galectin 9 Antibody - IHC of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-LGALS9 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
Select
LGALS9 / Galectin 9 Mouse anti-Human Monoclonal (OTI1D12) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
LGALS9 / Galectin 9 Antibody - Immunohistochemical staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-LGALS9 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min,
Select
LGALS9 / Galectin 9 Mouse anti-Human Monoclonal (Carrier-free) (OTI1D12) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
LGALS9 / Galectin 9 Antibody - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
LGALS9 / Galectin 9 Rabbit anti-Human Polyclonal (aa1-323) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
LGALS9 / Galectin 9 Antibody - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
LGALS9 / Galectin 9 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, IHC, IHC-P, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
LGALS9 / Galectin 9 Antibody - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
LGALS9 / Galectin 9 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, IHC, IHC-P, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
LGALS9 / Galectin 9 Antibody - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
LGALS9 / Galectin 9 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, IHC, IHC-P, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
LGALS9 / Galectin 9 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY LGALS9 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-LGALS9.
Select
LGALS9 / Galectin 9 Mouse anti-Human Monoclonal (OTI2E10) Antibody
Human
WB
Unconjugated
100 µl/$434
LGALS9 / Galectin 9 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY LGALS9. (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates. (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-LGALS9.
Select
LGALS9 / Galectin 9 Mouse anti-Human Monoclonal (Carrier-free) (OTI2E10) Antibody
Human
WB
Unconjugated, Carrier-free
100 µg/$511
LGALS9 / Galectin 9 Antibody - Western blot of recombinant LGALS9 / Galectin 9.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
LGALS9 / Galectin 9 Rabbit anti-Cow Polyclonal (aa17-148) Antibody
Mouse, Bovine, Cow
WB
Unconjugated
100 µl/$317; 200 µl/$362; 500 µl/$513; 1 ml/$589; 2 ml/$812; 5 ml/$1,324
LGALS9 / Galectin 9 Antibody - Immunohistochemistry of paraffin-embedded human kidney using antibody at 1:100 dilution.
Select
LGALS9 / Galectin 9 Rabbit anti-Human Polyclonal (aa1-240) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
LGALS9 / Galectin 9 Antibody - Western blot of Galectin-9 (G80) pAb in extracts from THP1 cells.
Select
LGALS9 / Galectin 9 Rabbit anti-Human Polyclonal (Gly80) Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
50 µl/$321; 100 µl/$403
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).