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LGALS7 / Galectin 7

lectin, galactoside-binding, soluble, 7

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Differential and in situ hybridizations indicate that this lectin is specifically expressed in keratinocytes. It is expressed at all stages of epidermal differentiation (i. e., in basal and suprabasal layers). It is moderately repressed by retinoic acid. The protein was found mainly in stratified squamous epithelium. The antigen localized to basal keratinocytes, although it was also found, albeit at lower levels, in the suprabasal layers where it concentrated to areas of cell-to-cell contact. The cellular localization and its striking down-regulation in cultured keratinocytes imply a role in cell-cell and/or cell-matrix interactions necessary for normal growth control.

Gene Name: lectin, galactoside-binding, soluble, 7
Synonyms: LGALS7, GAL7, Gal-7, Galectin 7, Galectin-7, p53-induced gene 1 protein, PIG1, TP53I1, HKL-14, LGALS7A, PI7
Target Sequences: NM_002307 NP_002298.1 P47929

Publications (1)

1
Galectin-7 as a potential predictive marker of chemo- and/or radio-therapy resistance in oral squamous cell carcinoma. Matsukawa S, Morita K, Negishi A, Harada H, Nakajima Y, Shimamoto H, Tomioka H, Tanaka K, Ono M, Yamada T, Omura K. Cancer medicine. 2014 3:349-61. (ICC; Human) [Full Text Article] [PubMed:24515895] [PMC:PMC3987084]

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Products
Proteins (14)
Over-Expression Lysate (2)
Recombinant (12)
LGALS7 / Galectin 7 (14)
No (14)
GST (1)
GST, N-terminus (1)
His (6)
His-T7 (1)
Myc-DDK (Flag) (3)
Human (8)
Mouse (4)
Rat (1)
293T Cells (1)
E. coli (9)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Yeast (1)
Purified (2)
Low endotoxin level (2)
LGALS7 / Galectin 7 Protein
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E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
Select
E. coli
GST, N-terminus
41.8 kDa
100 µg/$728; 20 µg/$360
LGALS7 / Galectin 7 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
14.9 kDa
100 µg/$494
Select
E. coli
His
19.1 kD
1 mg/$1,679; 100 µg/$500; 20 µg/$364
LGALS7 / Galectin 7 Protein - 12.5% SDS-PAGE of human LGALS7 stained with Coomassie Blue
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Wheat Germ Extract
GST
41.5 kDa
10 µg/$479; 25 µg/$670
LGALS7 / Galectin 7 Protein
Select
Yeast
His
17 kD
100 µg/$499; 20 µg/$364; 1 mg/$1,683
LGALS7 / Galectin 7 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
14.9 kDa
20 µg/$150
LGALS7 / Galectin 7 Protein - Purified recombinant protein LGALS7 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
14.9 kDa
20 µg/$1,107
Select
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
14.9 kDa
10 µg/$277; 50 µg/$389
LGALS7 / Galectin 7 Protein
Select
E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
Select
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
14.9kD
10 µg/$277; 50 µg/$395; 500 µg/$1,203; 1 mg/$1,627
LGALS7 / Galectin 7 Protein - Recombinant Galectin 7 By SDS-PAGE
Select
E. coli
His
16.3 kDa
10 µg/$265; 50 µg/$347; 100 µg/$545; 200 µg/$682; 1 mg/$1,690; 500 µg/$1,270; 5 mg/$2,637; 2 mg/$1,866
LGALS7 / Galectin 7 Protein - Recombinant Galectin 7 By SDS-PAGE
Select
E. coli
His-T7
18.6 kDa
50 µg/$382; 10 µg/$271; 200 µg/$762; 100 µg/$610; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998
LGALS7 / Galectin 7 Protein - Recombinant Galectin 7 By SDS-PAGE
Select
E. coli
His
15.6 kDa
10 µg/$259; 50 µg/$331; 100 µg/$482; 200 µg/$602; 1 mg/$1,553; 500 µg/$1,156; 5 mg/$2,481; 2 mg/$1,723
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).