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LGALS3 / Galectin 3
lectin, galactoside-binding, soluble, 3
LGALS3 / Galectin 3 is a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. The protein exhibits antimicrobial activity against bacteria and fungi. Alternate splicing results in multiple transcript variants.
| Gene Name: | lectin, galactoside-binding, soluble, 3 |
| Synonyms: | LGALS3, 35 kd lectin, 35 kDa lectin, CBP35, GAL3, Galactoside-binding protein, GALIG, IgE-binding protein, Laminin-binding protein, Gal-3, GALBP, MAC-2, Mac-2 antigen, L31, MAC2, CBP 35, Galactose-specific lectin 3, Galectin-3, L-31, Lectin L-29 |
| Target Sequences: | NM_002306 NP_002297.2 P17931 |
Publications (8)
1
Interaction of Vpx and apolipoprotein B mRNA-editing catalytic polypeptide 3 family member A (APOBEC3A) correlates with efficient lentivirus infection of monocytes. Berger A, Mnk C, Schweizer M, Cichutek K, Schle S, Flory E. The Journal of biological chemistry. 2010 285:12248-54.
[PubMed:20178977]
[PMC:PMC2852964]
2
AlphaB-crystallin is found in detergent-resistant membrane microdomains and is secreted via exosomes from human retinal pigment epithelial cells. Gangalum RK, Atanasov IC, Zhou ZH, Bhat SP. The Journal of biological chemistry. 2011 286:3261-9.
[PubMed:21097504]
[PMC:PMC3030331]
3
FOXE3 mutations predispose to thoracic aortic aneurysms and dissections. Kuang SQ, Medina-Martinez O, Guo DC, Gong L, Regalado ES, Reynolds CL, Boileau C, Jondeau G, Prakash SK, Kwartler CS, Zhu LY, Peters AM, Duan XY, Bamshad MJ, Shendure J, Nickerson DA, Santos-Cortez RL, Dong X, Leal SM, Majesky MW, Swindell EC, Jamrich M, Milewicz DM. The Journal of clinical investigation. 2016 126:948-61. (WB; Mouse)
[Full Text Article]
[PubMed:26854927]
[PMC:PMC4767350]
☰ Filters
Products
Antibodies
(184)
Type
Primary
(184)
Target
LGALS3 / Galectin 3
(184)
Reactivity
Human
(167)
Mouse
(55)
Rat
(35)
Bat
(3)
Dog
(1)
Gibbon
(3)
Pig
(3)
Application
IHC
(87)
IHC-Fr
(7)
IHC-P
(47)
WB
(163)
Flo
(13)
ELISA
(55)
Func
(3)
ICC
(6)
IF
(31)
IP
(8)
Peptide-ELISA
(4)
PMA
(4)
Host
rabbit
(97)
mouse
(84)
goat
(1)
rat
(2)
Product Group
IHCPlus
(7)
PathPlus Cancer
(2)
PathPlus Cancer Pathology
(2)
Isotype
IgG
(66)
IgG1
(38)
IgG1,k
(16)
IgG2a
(7)
IgG2a,k
(1)
IgG2b
(9)
Clonality
monoclonal mc
(86)
polyclonal pc
(98)
Clone
05
(1)
179
(1)
1A2
(1)
1G8
(2)
320CT4.5.2
(6)
3G7F11
(1)
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(1)
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(1)
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(1)
NIBJ756
(1)
NJK45
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NJKN46
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NLKMN2
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OTI15E4
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(2)
PWEJ45
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UMAB157
(2)
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(2)
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(4)
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(9)
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(4)
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(15)
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(20)
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(2)
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(4)
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(4)
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(12)
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(12)
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(9)
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(5)
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(1)
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(119)
Epitope
aa163-191
(14)
aa1-250
(8)
aa1-262
(8)
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(8)
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(7)
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(7)
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(5)
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(4)
110-190 aa, Internal
(1)
C-terminal
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Internal
(1)
aa1-58
(1)
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(1)
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(1)
aa141-190
(1)
aa151-251
(1)
aa153-264
(1)
aa155-168
(1)
aa2-250
(1)
Publications
No
(183)
Yes
(1)
Cancer Pathology
Cancer
LGALS3 / Galectin 3 Rabbit anti-Human Polyclonal (aa141-190) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
100 µl/$460
LGALS3 / Galectin 3 Goat anti-Mouse Polyclonal (aa155-168) Antibody
Mouse, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
Cancer Pathology
Cancer
LGALS3 / Galectin 3 Rabbit anti-Human Polyclonal (aa38-87) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
LGALS3 / Galectin 3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$396
LGALS3 / Galectin 3 Mouse anti-Human Monoclonal (52C1) Antibody
Mouse, Rat, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
50 µl/$460
LGALS3 / Galectin 3 Mouse anti-Human Monoclonal (1G8) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$460
LGALS3 / Galectin 3 Mouse anti-Human Monoclonal (B2C10) Antibody
Mouse, Human
Flo, Func, IHC, IHC-Fr, IHC-P, WB
Unconjugated
100 µg/$589
LGALS3 / Galectin 3 Mouse anti-Human Monoclonal (aa1-58) (A3A12) Antibody
Mouse, Rat, Human
ELISA, Flo, IHC, IHC-P, WB
Unconjugated
100 µg/$866
LGALS3 / Galectin 3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
LGALS3 / Galectin 3 Rabbit anti-Mouse Polyclonal (aa2-264) Antibody
Rat, Human
ICC, IHC-P, IP, WB
Unconjugated
50 µl/$460
LGALS3 / Galectin 3 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC, WB
Unconjugated
200 µl/$468
LGALS3 / Galectin 3 Rabbit anti-Mouse Polyclonal (aa153-264) Antibody
Mouse, Rat
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
LGALS3 / Galectin 3 Rabbit anti-Human Polyclonal (aa163-191) Antibody
Human
ELISA, Flo, WB
Unconjugated
200 µl/$734
LGALS3 / Galectin 3 Mouse anti-Human Monoclonal Antibody
Human
ELISA, IP, WB
Unconjugated
100 µl/$412
LGALS3 / Galectin 3 Mouse anti-Human Monoclonal (Concentrated) (B2C10) Antibody
Human
Flo, Func, IHC, IHC-Fr, IHC-P, WB
Unconjugated, Concentrated
50 µg/$565
LGALS3 / Galectin 3 Rabbit anti-Human Polyclonal (C-terminal) Antibody
Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
LGALS3 / Galectin 3 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$299
LGALS3 / Galectin 3 Rabbit anti-Human Polyclonal (110-190 aa, Internal) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
LGALS3 / Galectin 3 Mouse anti-Human Monoclonal (B2C10) Antibody
Mouse, Human
Flo, Func, IHC, IHC-Fr, IHC-P, WB
Unconjugated
100 µg/$862
LGALS3 / Galectin 3 Rat anti-Mouse Monoclonal (Biotin) (M3/38) Antibody
Mouse
ELISA, Flo, IHC, IHC-Fr, IHC-P
Biotin Conjugated
100 µg/$357
LGALS3 / Galectin 3 Mouse anti-Human Monoclonal (A3A12) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
100 µg/$1,215
LGALS3 / Galectin 3 Mouse anti-Human Monoclonal (Concentrated) (9C4) Antibody
Human
IHC, IHC-Fr, IHC-P
Unconjugated, Concentrated
1 ml/$1,292
LGALS3 / Galectin 3 Mouse anti-Human Monoclonal Antibody
Human
ELISA, WB
Unconjugated
20 µg/$242; 100 µg/$304; 200 µg/$334; 500 µg/$452
LGALS3 / Galectin 3 Rabbit anti-Mouse Polyclonal (aa138-167) (Azide-free) (HRP) Antibody
Mouse
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
LGALS3 / Galectin 3 Mouse anti-Human Monoclonal (OTI1A3) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
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of 184
product results
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