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LGALS1 / Galectin 1

lectin, galactoside-binding, soluble, 1

May regulate apoptosis, cell proliferation and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis.

Gene Name:	lectin, galactoside-binding, soluble, 1
Synonyms:	LGALS1, 14 kDa lectin, 14 kDa laminin-binding protein, 14 kd lectin, GAL1, Galectin 1, Galectin-1, HBL, Lactose-binding lectin 1, Galaptin, GBP, HLBP14, HPL, S-Lac lectin 1, Gal-1
Target Sequences:	NM_002305 NP_002296.1 P09382

Publications (2)

The molecular basis of wound healing processes induced by lithospermi radix: a proteomics and biochemical analysis. Hsiao CY, Tsai TH, Chak KF. Evidence-based complementary and alternative medicine : eCAM. 2012 2012:508972. [PubMed:23024692] [PMC:PMC3457683] Related Antibodies: LS-C166519.

Galectin-1 suppression delineates a new strategy to inhibit myeloma-induced angiogenesis and tumoral growth in vivo. P Storti, V Marchica, I Airoldi, G Donofrio, E Fiorini, V Ferri, D Guasco, K Todoerti, R Silbermann, J L Anderson, W Zhao, L Agnelli, M Bolzoni, E Martella, C Mancini, N Campanini, D M Noonan, P G Petronini, A Neri, F Aversa, G D Roodman, N Giuliani. Leukemia. 2016 December;30:2351-2363. [Full Text Article] [PubMed:27311934]

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