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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Cell Cycle Pathways
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Leptin

Leptin is a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development.

Gene Name: Leptin
Synonyms: LEP, Leptin, LEPD, Obese protein, Obese, mouse, homolog of, Obesity factor, OBS, OB
Target Sequences: NM_000230 NP_000221.1 P41159

Publications (3)

1
Leptin as a potential target for estrogen receptor-positive breast cancer. Yom CK, Lee KM, Han W, Kim SW, Kim HS, Moon BI, Jeong KY, Im SA, Noh DY. Journal of breast cancer. 2013 16:138-45. (WB; Human) [Full Text Article] [PubMed:23843844] [PMC:PMC3706857] Related Antibodies: LS-C25172.
2
Hypoplastic left heart syndrome is associated with structural and vascular placental abnormalities and leptin dysregulation. Jones HN, Olbrych SK, Smith KL, Cnota JF, Habli M, Ramos-Gonzales O, Owens KJ, Hinton AC, Polzin WJ, Muglia LJ, Hinton RB. Placenta. 2015 36:1078-86. (WB; Mouse) [Full Text Article] [PubMed:26278057] Related Antibodies: LS-B1459.
3
Delta-like protein 1 in the pituitary-adipose axis in the adult male mouse. Bello AR, Puertas-Avendaño RA, González-Gómez MJ, González-Gómez M, Laborda J, Damas C, Ruiz-Hidalgo M, Diaz C. Journal of neuroendocrinology. 2017 August;29: [Full Text Article] [PubMed:28718206] [PMC:PMC6084355]

Filtered by: None
Target
Leptin (232)
Reactivity
Human (130)
Mouse (77)
Rat (61)
Bat (1)
Bovine (24)
Chicken (4)
Chimpanzee (7)
Cow (16)
Dog (8)
Gibbon (8)
Goat (5)
Hamster (9)
Horse (17)
Macaque (2)
Monkey (6)
Orangutan (4)
Pig (2)
Rabbit (4)
Sheep (5)
Application
IHC (45)
IHC-Fr (1)
IHC-P (18)
WB (181)
Flo (8)
ELISA (128)
ICC (20)
IF (15)
IP (13)
Peptide-ELISA (1)
RIA (1)
Host
rabbit (158)
mouse (48)
goat (15)
chicken (2)
rat (8)
sheep (1)
Isotype
IgG (102)
IgG1 (20)
IgG1,k (12)
IgG2a,k (1)
IgG2b,k (4)
Clonality
monoclonal mc (56)
polyclonal pc (176)
Clone
10H1 (1)
11 (2)
13A127 (1)
3G1-1C9 (1)
3G7 (2)
4F12 (1)
4F8 (1)
5F10 (1)
6 (1)
9C10 (3)
AT7E10 (1)
C10 (8)
C4 (8)
LEP-02 (1)
PAT7E10AT (1)
RLEP 227 (1)
YD-HLEP4B6 (2)
Format
AP Conjugated (9)
APC (8)
APC Conjugated (12)
Azide-free (2)
Biotin Conjugated (31)
Cy3 Conjugated (8)
Cy7 Conjugated (8)
FITC Conjugated (20)
HRP Conjugated (19)
PE Conjugated (16)
Preservative Free (2)
Unconjugated (109)
Epitope
aa22-167 (35)
aa134-166 (8)
aa15-141 (8)
aa29-160 (8)
aa8-37 (8)
N-Terminus (5)
C-Terminus (4)
aa116-167 (2)
aa22-56 (2)
aa57-92 (2)
Lys36 (1)
N-Terminal (1)
aa1-24 (1)
aa25-208 (1)
aa36-85 (1)
aa57-70 (1)
aa74-109 (1)
Publications
No (230)
Yes (2)
Showing 1-25 of 232 results

IHC-plus™ Leptin Antibody LS-B1459
Publications (1)
Publications (1)
Rabbit Polyclonal to Mouse Leptin
Mouse, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50µl 85mg/ml  $425.00
Anti-LEP / Leptin antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

IHC-plus™ Leptin Antibody LS-B8192
Mouse Monoclonal (IgG1,k) to Human Leptin
Human
ELISA, IHC, IHC-P, WB
Unconjugated
500µg 1mg/ml  $425.00
Human, Kidney:Formalin-Fixed Paraffin-Embedded (FFPE)
Anti-Human Leptin Western Blot Unreduced

IHC-plus™ Leptin Antibody (C-Terminus) LS-B4652
Rabbit Polyclonal to Human Leptin
Chicken, Sheep, Bovine, Mouse, Goat, Dog, Rat, Hamster, Horse, Human, Monkey
IHC, IHC-P, WB
Unconjugated
100µl 0.5mg/ml  $485.00
Anti-LEP / Leptin antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
LEP / Leptin antibody Western blot of HepG2 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

IHC-plus™ Leptin Antibody (N-Terminus) LS-B4651
Rabbit Polyclonal (IgG) to Human Leptin
Rabbit, Mouse, Dog, Bovine, Hamster, Horse, Human
IHC, IHC-P, WB
Unconjugated
100µl  $485.00
Anti-LEP / Leptin antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
LEP / Leptin antibody Western blot of Fetal Small Intestine lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Leptin Antibody (clone 3G1-1C9) LS-C197610
Mouse Monoclonal [clone 3G1-1C9] (IgG2b,k) to Human Leptin
Human
ELISA, WB
Unconjugated
100µg  $365.00
Detection limit for recombinant GST tagged LEP is approximately 0.1 ng/ml as a capture antibody.

Leptin Antibody LS-C104376
Goat Polyclonal to Rat Leptin
Rat
ELISA, WB
Unconjugated
50µg  $285.00; 100µg  $325.00
Western Blot (non-reducing) of Leptin antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western Blot (reducing) of Leptin antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Leptin Antibody (Biotin) LS-C104375
Goat Polyclonal to Rat Leptin
Rat
ELISA, WB
Biotin Conjugated
25µg  $285.00; 50µg  $325.00
Western Blot (non-reducing) of Leptin antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western Blot (reducing) of Leptin antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Leptin Antibody (aa8-37) LS-C322635
Rabbit Polyclonal (IgG) to Human Leptin
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
200µl  $590.00

Leptin Antibody (aa8-37, FITC) LS-C261829
Rabbit Polyclonal (IgG) to Human Leptin
Human
ELISA, Flo, ICC, IF, IHC, WB
FITC Conjugated
200µl  $740.00

Leptin Antibody (aa8-37, PE) LS-C261830
Rabbit Polyclonal (IgG) to Human Leptin
Human
ELISA, Flo, ICC, IF, IHC, WB
PE Conjugated
200µl  $740.00

Leptin Antibody (aa8-37, APC) LS-C261826
Rabbit Polyclonal (IgG) to Human Leptin
Human
ELISA, Flo, ICC, IF, IHC, WB
APC Conjugated
200µl  $740.00

Leptin Antibody (aa8-37, Azide-free, HRP) LS-C261827
Rabbit Polyclonal (IgG) to Human Leptin
Human
ELISA, Flo, ICC, IF, IHC, WB
HRP Conjugated, Azide-free
200µl  $740.00

Leptin Antibody LS-C104645
Rabbit Polyclonal to Human Leptin
Human
ELISA, WB
Unconjugated
50µg  $285.00; 100µg  $325.00
Western Blot (non-reducing) of Leptin antibody
Western Blot (reducing) of Leptin antibody

Leptin Antibody LS-C104760
Rabbit Polyclonal to Mouse Leptin
Mouse
ELISA, WB
Unconjugated
50µg  $285.00; 100µg  $325.00
Western Blot (non-reducing) of Leptin antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western Blot (reducing) of Leptin antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Leptin Antibody LS-C25172
Publications (1)
Publications (1)
Rabbit Polyclonal (IgG) to Human Leptin
Human
WB
Unconjugated
250µg  $455.00

Leptin Antibody (aa8-37) LS-C165743
Rabbit Polyclonal to Human Leptin
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
400µl  $325.00
LEP Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human placenta tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
Confocal immunofluorescence of LEP Antibody with HeLa cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).

Leptin Antibody (aa29-160) LS-C314373
Rabbit Polyclonal to Cow Leptin
Bovine, Cow
WB
Unconjugated
20µl 0.5mg/ml  $205.00; 100µl 0.5mg/ml  $265.00; 200µl 0.5mg/ml  $315.00; 1ml 0.5mg/ml  $560.00
Western blot of recombinant Leptin.

Leptin Antibody (N-Terminus) LS-C37164
Rabbit Polyclonal to Human Leptin
Mouse, Rat, Pig, Human, Monkey
ELISA, IP, RIA, WB
Unconjugated
100µl  $475.00

Leptin Antibody (clone YD-HLEP4B6) LS-C25161
Mouse Monoclonal [clone YD-HLEP4B6] (IgG1) to Human Leptin
Human
ELISA, IP, WB
Unconjugated
500µg  $515.00; 1mg  $755.00

Leptin Antibody (clone YD-HLEP4B6) LS-C760498
Mouse Monoclonal [clone YD-HLEP4B6] (IgG1) to Human Leptin
Human
ELISA, IP, WB
Unconjugated
0.5mg  $335.00; 1mg  $445.00

Leptin Antibody (aa74-109) LS-C407870
Rabbit Polyclonal to Mouse Leptin
Mouse
ELISA, WB
Unconjugated
100µg  $325.00
Leptin antibody Western blot. All lanes: Anti LEP/leptin at 0.5 ug/ml. WB: NIH3T3 Whole Cell Lysate at 40 ug. Predicted band size: 16 kD. Observed band size: 16 kD.

Leptin Antibody (aa36-85) LS-C199952
Rabbit Polyclonal (IgG) to Human Leptin
Mouse, Rat, Human
IHC, Peptide-ELISA
Unconjugated
50µl 1mg/ml  $265.00; 100µl 1mg/ml  $325.00
Immunohistochemistry analysis of Ob antibody in paraffin-embedded human breast carcinoma tissue.

Leptin Antibody (clone 4F12) LS-C52179
Mouse Monoclonal [clone 4F12] (IgG1) to Human Leptin
Human
ELISA
Unconjugated
200µg 5.2mg/ml  $395.00

Leptin Antibody (aa22-167, clone C4) LS-C314150
Rat Monoclonal [clone C4] (IgG) to Mouse Leptin
Mouse
WB
Unconjugated
20µl 1mg/ml  $205.00; 100µl 1mg/ml  $255.00; 200µl 1mg/ml  $295.00; 1ml 1mg/ml  $515.00
Western Blot; Sample: Recombinant LEP, Mouse.

Leptin Antibody LS-C807251
Rabbit Polyclonal (IgG) to Human Leptin
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100µl 1mg/ml  $325.00; 200µl 1mg/ml  $375.00
Immunohistochemistry Image
Western blot Image
Showing 1-25 of 232 results

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PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).