LECT1 / Chondromodulin-I

leukocyte cell derived chemotaxin 1

LECT1 / Chondromodulin-I is a glycosylated transmembrane protein that is cleaved to form a mature, secreted protein. The N-terminus of the precursor protein shares characteristics with other surfactant proteins and is sometimes called chondrosurfactant protein although no biological activity has yet been defined for it. The C-terminus of the precursor protein contains a 25 kDa mature protein called leukocyte cell-derived chemotaxin-1 or chondromodulin-1. The mature protein promotes chondrocyte growth and inhibits angiogenesis. This gene is expressed in the avascular zone of prehypertrophic cartilage and its expression decreases during chondrocyte hypertrophy and vascular invasion. The mature protein likely plays a role in endochondral bone development by permitting cartilaginous anlagen to be vascularized and replaced by bone. It may be involved also in the broad control of tissue vascularization during development. Alternative splicing results in multiple transcript variants encoding different isoforms.

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Products

Proteins (10)

Type

Over-Expression Lysate (2)

Recombinant (8)

Target

LECT1 / Chondromodulin-I (10)

Application

SDS-PAGE (1)

Publications

No (10)

Tag

6His, N-terminus (1)

6His-SUMO, N-terminus (1)

Fc (1)

GST (1)

His (2)

His-T7 (1)

Human IgG1 Fc, N-terminus (1)

Myc-DDK (Flag) (2)

Species

Human (9)

Source

293T Cells (1)

E. coli (5)

HEK 293 Cells (2)

Human Cells (1)

Wheat Germ Extract (1)

Purification

Purified (5)

Low Endotoxin Level

Low endotoxin level (2)

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Human LECT1 / Chondromodulin-I Protein (Recombinant Human IgG1 Fc, N-terminus) (Glu215-Val333) - LS-G51008

Source:

HEK 293 Cells

Tag:

Human IgG1 Fc, N-terminus

Application:

SDS-PAGE

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

The recombinant human LECT1 consists 379 amino acids and predicts a molecular mass of 42.1 kDa.

Price:

100 µg/$403

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Human LECT1 / Chondromodulin-I Protein (Recombinant 6His-SUMO, N-terminus) (aa215-334) - LS-G56374

Source:

E. coli

Tag:

6His-SUMO, N-terminus

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human LECT1 / Chondromodulin-I Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G87245

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

36.97 kDa

Price:

20 µg/$150

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Human LECT1 / Chondromodulin-I Protein (Recombinant Fc) (Glu215-Val333) - LS-G97653

Source:

Human Cells

Tag:

Fc

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

42.1 kDa

Price:

100 µg/$600

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Human LECT1 / Chondromodulin-I Protein (Recombinant His-T7) (aa134-334) - LS-G14978

Source:

E. coli

Tag:

His-T7

Molecular Weight:

26.8 kDa

Price:

10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176

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Human LECT1 / Chondromodulin-I Protein (Recombinant GST) (Full Length) - LS-G32480

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

63.5 kDa

Price:

2 µg/$439

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Human LECT1 / Chondromodulin-I Protein (Recombinant 6His, N-terminus) (Glu215-Val334) - LS-G26562

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

16.1 kDa

Price:

10 µg/$265; 50 µg/$315; 100 µg/$365; 200 µg/$484

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LECT1 / Chondromodulin-I Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G114917

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

36.97 kDa

Price:

100 µg/$494

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Human LECT1 / Chondromodulin-I Protein (Recombinant His) - LS-G2737

Source:

E. coli

Tag:

His

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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Human LECT1 / Chondromodulin-I Protein (Recombinant His) - LS-G2751

Source:

E. coli

Tag:

His

Price:

100 µg/$411; 500 µg/$985; 20 µg/$276

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