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LDB2
LIM domain binding 2
LDB2 belongs to the LIM-domain binding family. Members of this family are characterized by a conserved nuclear localization sequence, an amino-terminal homodimerization domain and a carboxy-terminal LIM interaction domain. These proteins function as adapter molecules to allow assembly of transcriptional regulatory complexes. Genetic association studies suggest functions for this gene in rhegmatogenous retinal detachment and coronary artery disease. Alternative splicing results in multiple transcript variants.
| Gene Name: | LIM domain binding 2 |
| Synonyms: | LDB2, CLIM-1, CLIM1, LIM binding domain 2, LIM domain binding 2, LIM domain-binding protein 2, LDB-2, LIM domain-binding factor-2 |
| Target Sequences: | NM_001290 NP_001281.1 O43679 |
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