LCN2 / Lipocalin 2 / NGAL

lipocalin 2

Iron-trafficking protein involved in multiple processes such as apoptosis, innate immunity and renal development. Binds iron through association with 2,5-dihydroxybenzoic acid (2,5-DHBA), a siderophore that shares structural similarities with bacterial enterobactin, and delivers or removes iron from the cell, depending on the context. Iron-bound form (holo-24p3) is internalized following binding to the SLC22A17 (24p3R) receptor, leading to release of iron and subsequent increase of intracellular iron concentration. In contrast, association of the iron-free form (apo-24p3) with the SLC22A17 (24p3R) receptor is followed by association with an intracellular siderophore, iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration. Involved in apoptosis due to interleukin-3 (IL3) deprivation: iron-loaded form increases intracellular iron concentration without promoting apoptosis, while iron-free form decreases intracellular iron levels, inducing expression of the proapoptotic protein BCL2L11/BIM, resulting in apoptosis. Involved in innate immunity, possibly by sequestrating iron, leading to limit bacterial growth.

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Products

ELISA Kits (42)

Type

Competitive EIA (2)

Custom (1)

Development Kit (3)

Sandwich (31)

Sandwich CLIA (5)

Target

LCN2 / Lipocalin 2 / NGAL (42)

Reactivity

Human (14)

Mouse (11)

Rat (8)

Canine (2)

Monkey (2)

Pig (3)

Rabbit (2)

Product Group

DevKit DuoPlus (3)

Format

12 x 8-Well Microstrips (4)

96-Well Microplate (11)

96-Well Strip Plate (24)

Antibody Pair and Standard (3)

Publications

No (41)

Yes (1)

Sample Type

Cell Culture Supernatants (20)

Cell Lysates (11)

Plasma (41)

Saliva (1)

Serum (41)

Tissue Homogenates (18)

Urine (15)

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Human LCN2 / Lipocalin 2 / NGAL (Sandwich ELISA) ELISA Kit - LS-F2720

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

156 - 10000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Saliva, Serum, Urine

Price:

1 Plate/$636

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Human LCN2 / Lipocalin 2 / NGAL (CLIA) ELISA Kit - LS-F26058

Type:

Sandwich CLIA

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

27.43 - 20000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates, Urine

Price:

1 Plate/$968

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Monkey LCN2 / Lipocalin 2 / NGAL (Sandwich ELISA) ELISA Kit - LS-F38530

(4.0) Rating

(1) Publication(s)

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

0.31 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$863

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Monkey LCN2 / Lipocalin 2 / NGAL (Sandwich ELISA) ELISA Kit - LS-F56370

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Mouse LCN2 / Lipocalin 2 / NGAL (Sandwich ELISA) ELISA Kit - LS-F4586

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates, Urine

Price:

1 Plate/$573

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Rat LCN2 / Lipocalin 2 / NGAL (Sandwich ELISA) ELISA Kit - LS-F516

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Rat

Range:

32.77 - 3200 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$700

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Human LCN2 / Lipocalin 2 / NGAL (Sandwich ELISA) ELISA Kit - LS-F456

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

4.1 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$588

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Human LCN2 / Lipocalin 2 / NGAL (Sandwich ELISA) ELISA Kit - LS-F24634

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$669

Select

Pig LCN2 / Lipocalin 2 / NGAL (Sandwich ELISA) ELISA Kit - LS-F36440

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Pig

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Human LCN2 / Lipocalin 2 / NGAL (Sandwich ELISA) ELISA Kit - LS-F4329

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates, Urine

Price:

1 Plate/$585

Select

Mouse LCN2 / Lipocalin 2 / NGAL (CLIA) ELISA Kit - LS-F30873

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Mouse

Range:

15.63 - 1000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$728

Select

Mouse LCN2 / Lipocalin 2 / NGAL (Sandwich ELISA) ELISA Kit - LS-F2721

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Mouse

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum, Urine

Price:

1 Plate/$636

Select

Rat LCN2 / Lipocalin 2 / NGAL (Sandwich ELISA) ELISA Kit - LS-F2722

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Rat

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum, Urine

Price:

1 Plate/$636

Select

Mouse LCN2 / Lipocalin 2 / NGAL (CLIA) ELISA Kit - LS-F26059

Type:

Sandwich CLIA

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

27.43 - 20000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates, Urine

Price:

1 Plate/$990

Select

Rat LCN2 / Lipocalin 2 / NGAL (Sandwich ELISA) ELISA Kit - LS-F27530

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

5 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$913

Select

Pig LCN2 / Lipocalin 2 / NGAL (Sandwich ELISA) ELISA Kit - LS-F5276

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Pig

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$929

Select

DevKit DuoPlus Canine LCN2 / Lipocalin 2 / NGAL ELISA Development Kit - LS-F72249

Type:

Development Kit

Format:

Antibody Pair and Standard

Reactivity:

Canine

Range:

3.12 - 200 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

500 Wells/$1,356; 1000 Wells/$2,037

Select

Mouse LCN2 / Lipocalin 2 / NGAL (Custom ELISA) ELISA Kit - LS-F17068

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$685

Select

Human LCN2 / Lipocalin 2 / NGAL (CLIA) ELISA Kit - LS-F29138

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

31.25 - 2000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$728

Select

Pig LCN2 / Lipocalin 2 / NGAL (Sandwich ELISA) ELISA Kit - LS-F21671

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Pig

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$728

Select

Rat LCN2 / Lipocalin 2 / NGAL (Sandwich ELISA) ELISA Kit - LS-F23897

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Rat

Range:

62.5 - 4000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

Select

Rabbit LCN2 / Lipocalin 2 / NGAL (Sandwich ELISA) ELISA Kit - LS-F24119

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Rabbit

Range:

78.125 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$728

Select

Human LCN2 / Lipocalin 2 / NGAL (Sandwich ELISA) ELISA Kit - LS-F24635

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

156 - 10000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$669

Select

Mouse LCN2 / Lipocalin 2 / NGAL (Sandwich ELISA) ELISA Kit - LS-F23715

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Mouse

Range:

39.063 - 2500 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

Select

Rat LCN2 / Lipocalin 2 / NGAL (Sandwich ELISA) ELISA Kit - LS-F24968

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum, Urine

Price:

1 Plate/$669

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