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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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LCN2 / Lipocalin 2 / NGAL

lipocalin 2

Iron-trafficking protein involved in multiple processes such as apoptosis, innate immunity and renal development. Binds iron through association with 2,5-dihydroxybenzoic acid (2,5-DHBA), a siderophore that shares structural similarities with bacterial enterobactin, and delivers or removes iron from the cell, depending on the context. Iron-bound form (holo-24p3) is internalized following binding to the SLC22A17 (24p3R) receptor, leading to release of iron and subsequent increase of intracellular iron concentration. In contrast, association of the iron-free form (apo-24p3) with the SLC22A17 (24p3R) receptor is followed by association with an intracellular siderophore, iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration. Involved in apoptosis due to interleukin-3 (IL3) deprivation: iron-loaded form increases intracellular iron concentration without promoting apoptosis, while iron-free form decreases intracellular iron levels, inducing expression of the proapoptotic protein BCL2L11/BIM, resulting in apoptosis. Involved in innate immunity, possibly by sequestrating iron, leading to limit bacterial growth.

Gene Name: lipocalin 2
Synonyms: LCN2, 24p3, HNL, Lipocalin 2, Lipocalin-2, MSFI, Siderocalin LCN2, NGAL, p25, Lipocalin 2 (oncogene 24p3), Oncogene 24p3
Target Sequences: NM_005564 NP_005555.2 P80188

Viewing 1-25 of 192 items
LCN2 / Lipocalin 2 / NGAL Antibody - Anti-LCN2 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Select
(3) Publication(s)
Goat Polyclonal to Human LCN2 / Lipocalin 2 / NGAL
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50µg   0.5mg/ml   $425.00
LCN2 / Lipocalin 2 / NGAL Antibody - Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Rabbit Polyclonal (IgG) to Human LCN2 / Lipocalin 2 / NGAL
Mouse, Human
IF, IHC-P, WB
Unconjugated
50µl   $425.00
LCN2 / Lipocalin 2 / NGAL Antibody - Anti-LCN2 / Lipocalin 2 / NGAL antibody IHC staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml.
Select
Mouse Monoclonal (IgG2b) to Human LCN2 / Lipocalin 2 / NGAL
Human
ELISA, IHC, IHC-P, WB
Unconjugated
100µg   $485.00
LCN2 / Lipocalin 2 / NGAL Antibody - Anti-LCN2 / Lipocalin 2 / NGAL antibody IHC staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal (IgG) to Human LCN2 / Lipocalin 2 / NGAL
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50µg   $425.00
LCN2 / Lipocalin 2 / NGAL Antibody - Anti-LCN2 / Lipocalin 2 / NGAL antibody IHC staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal (IgG) to Human LCN2 / Lipocalin 2 / NGAL
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50µg   $425.00
Select
Mouse Monoclonal [clone 5G5] (IgG1,k) to Human LCN2 / Lipocalin 2 / NGAL
Human
ELISA, IHC, IHC-Pfa, WB
Unconjugated
100µl   $980.00
Select
Mouse Monoclonal (IgG1,k) to Human LCN2 / Lipocalin 2 / NGAL
Human
ELISA, IHC, SwELISA, WB
Unconjugated
100µl   $980.00
LCN2 / Lipocalin 2 / NGAL Antibody - Immunohistochemistry of paraffin-embedded Human breast cancer using LCN2 Polyclonal Antibody at dilution of 1:60.
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Rabbit Polyclonal (IgG) to Human LCN2 / Lipocalin 2 / NGAL
Human
ELISA, IHC, WB
Unconjugated
20µl   0.6mg/ml   $205.00; 60µl   0.6mg/ml   $235.00; 120µl   0.6mg/ml   $295.00; 200µl   0.6mg/ml   $395.00
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Mouse Monoclonal [clone GF1] (IgG1,k) to Human LCN2 / Lipocalin 2 / NGAL
Human
ELISA, WB
Unconjugated
100µl   $1,005.00
LCN2 / Lipocalin 2 / NGAL Antibody - Western blot of recombinant LCN2 / Lipocalin 2 / NGAL.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Rabbit Polyclonal to Mouse LCN2 / Lipocalin 2 / NGAL
Mouse
WB
Unconjugated
20µl   0.5mg/ml   $205.00; 100µl   0.5mg/ml   $255.00; 200µl   0.5mg/ml   $295.00; 1ml   0.5mg/ml   $515.00
LCN2 / Lipocalin 2 / NGAL Antibody - Antibody (2 ug/ml) staining of Mouse Kidney lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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Goat Polyclonal to Mouse LCN2 / Lipocalin 2 / NGAL
Mouse
Peptide-ELISA, WB
Unconjugated
100µg   0.5mg/ml   $405.00
Select
Goat Polyclonal (IgG) to Rat LCN2 / Lipocalin 2 / NGAL
Mouse, Rat
ELISA, IP, WB
Unconjugated
100µg   $785.00
LCN2 / Lipocalin 2 / NGAL Antibody - Lipocalin 2 antibody IHC-paraffin. IHC(P): Mouse Spleen Tissue.
Select
Rabbit Polyclonal to Mouse LCN2 / Lipocalin 2 / NGAL
Mouse, Rat
ELISA, IHC, IHC-P, WB
Unconjugated
100µg   $355.00
Select
Mouse Monoclonal [clone 697] (IgG1) to Human LCN2 / Lipocalin 2 / NGAL
Human
IF
Unconjugated
100µg   $575.00
Select
Mouse Monoclonal (IgG1,k) to Rat LCN2 / Lipocalin 2 / NGAL
Rat
ELISA, WB
Unconjugated
50µl   $860.00; 100µl   $1,080.00
Select
Rabbit Polyclonal (IgG) to Human LCN2 / Lipocalin 2 / NGAL
Human
IP, WB
Unconjugated
100µl   $605.00
Select
Rabbit Polyclonal to Mouse LCN2 / Lipocalin 2 / NGAL
Mouse, Rat, Human
WB
Unconjugated
30µg   $245.00; 100µg   $435.00
LCN2 / Lipocalin 2 / NGAL Antibody - Western blot of recombinant LCN2 / Lipocalin 2 / NGAL.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Dog LCN2 / Lipocalin 2 / NGAL
Dog
WB
Unconjugated
20µl   0.5mg/ml   $205.00; 100µl   0.5mg/ml   $265.00; 200µl   0.5mg/ml   $315.00; 1ml   0.5mg/ml   $575.00
LCN2 / Lipocalin 2 / NGAL Antibody - Western blot of LCN2 / Lipocalin 2 / NGAL antibody.
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Rabbit Polyclonal to Pig LCN2 / Lipocalin 2 / NGAL
Pig
WB
Unconjugated
20µl   0.5mg/ml   $205.00; 100µl   0.5mg/ml   $275.00; 200µl   0.5mg/ml   $325.00; 1ml   0.5mg/ml   $605.00
Select
Rabbit Monoclonal [clone 023] (IgG) to Rat LCN2 / Lipocalin 2 / NGAL
Rat
ELISA
Unconjugated, Preservative Free
50µl   $245.00; 100µl   $305.00
LCN2 / Lipocalin 2 / NGAL Antibody - Lipocalin 2 antibody IHC-paraffin. IHC(P): Mouse Spleen Tissue.
Select
Rabbit Polyclonal to Rat LCN2 / Lipocalin 2 / NGAL
Mouse, Rat
ELISA, IHC, IHC-P, WB
Unconjugated
100µg   $355.00
LCN2 / Lipocalin 2 / NGAL Antibody
Select
Rat Monoclonal [clone 29] (IgG1,k) to Mouse LCN2 / Lipocalin 2 / NGAL
Mouse
ELISA, IHC, IHC-P, WB
Unconjugated
200µl   1mg/ml   $680.00; 1ml   1mg/ml   $3,060.00
LCN2 / Lipocalin 2 / NGAL Antibody - Lipocalin 2 antibody IHC-paraffin. IHC(P): Human Intestinal Cancer Tissue.
Select
Rabbit Polyclonal to Human LCN2 / Lipocalin 2 / NGAL
Rat, Human
ELISA, IHC, IHC-P, WB
Unconjugated
100µg   $355.00
LCN2 / Lipocalin 2 / NGAL Antibody
Select
Mouse Monoclonal [clone 28] (IgG1,k) to Pig LCN2 / Lipocalin 2 / NGAL
Pig
ELISA, IHC, IHC-P, WB
Unconjugated
200µl   1mg/ml   $680.00; 1ml   1mg/ml   $3,060.00
LCN2 / Lipocalin 2 / NGAL Antibody
Select
Rabbit Polyclonal (IgG) to Mouse LCN2 / Lipocalin 2 / NGAL
Mouse, Rat
IHC, IHC-P, WB
Unconjugated
100µg   $435.00

Viewing 1-25 of 192 items


If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).