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LAT2 / NTAL

linker for activation of T cells family, member 2

Involved in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. May also be involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and FCGR1 (high affinity immunoglobulin gamma Fc receptor I)-mediated signaling in myeloid cells. Couples activation of these receptors and their associated kinases with distal intracellular events through the recruitment of GRB2.

Gene Name: linker for activation of T cells family, member 2
Synonyms: LAT2, HSPC046, Non-T-cell activation linker, NTAL, LAB, WBSCR15, WBS15, WBSCR5, WSCR5
Target Sequences: NM_022040 NP_115853.2 Q9GZY6

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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).