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LAMP2 / CD107b

lysosomal-associated membrane protein 2

Implicated in tumor cell metastasis. May function in protection of the lysosomal membrane from autodigestion, maintenance of the acidic environment of the lysosome, adhesion when expressed on the cell surface (plasma membrane), and inter- and intracellular signal transduction. Protects cells from the toxic effects of methylating mutagens.

Gene Name: lysosomal-associated membrane protein 2
Family/Subfamily: Cancer
Synonyms: LAMP2, CD107b, CD107b antigen, LAMPB, LGP110, LAMP-2
Target Sequences: NM_013995 NP_054701.1 P13473

Publications (3)

1
A missense change in the ATG4D gene links aberrant autophagy to a neurodegenerative vacuolar storage disease. Kyöstilä K, Syrjä P, Jagannathan V, Chandrasekar G, Jokinen TS, Seppälä EH, Becker D, Drögemüller M, Dietschi E, Drögemüller C, Lang J, Steffen F, Rohdin C, Jäderlund KH, Lappalainen AK, Hahn K, Wohlsein P, Baumgärtner W, Henke D, Oevermann A, Kere J, Lohi H, Leeb T. PLoS genetics. 2015 11:e1005169. (IHC; Canine) [Full Text Article] [PubMed:25875846] [PMC:PMC4398399]
2
Databases for technical aspects of immunohistochemistry. Furukawa S, Nagaike M, Ozaki K. Journal of toxicologic pathology. 2017 30:79-107. (IHC; Canine) [Full Text Article] [PubMed:28190929] [PMC:PMC5293696]
3
Basal Autophagy Is Altered in Lagotto Romagnolo Dogs with an ATG4D Mutation. Pernilla Syrjä, Tahira Anwar, Tarja Jokinen, Kaisa Kyöstilä, Karin Hultin Jäderlund, Francesca Cozzi, Cecilia Rohdin, Kerstin Hahn, Peter Wohlsein, Wolfgang Baumgärtner, Diana Henke, Anna Oevermann, Antti Sukura, Tosso Leeb, Hannes Lohi, Eeva-Liisa Eskelinen. Veterinary pathology. 2017 Nov;54:953-963. [Full Text Article] [PubMed:28583040]

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Products
Proteins (13)
Over-Expression Lysate (2)
Recombinant (11)
LAMP2 / CD107b (13)
No (13)
6His, C-terminus (2)
GST, N-terminus (1)
His (3)
His-GST (2)
Myc-DDK (Flag) (5)
Human (9)
Mouse (2)
Rat (1)
293T Cells (1)
E. coli (4)
HEK 293 Cells (4)
Human Cells (2)
Mammalian Cells (1)
Wheat Germ Extract (1)
Purified (1)
Low endotoxin level (3)
Select
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
33.94kD
10 µg/$269; 50 µg/$372; 500 µg/$1,585; 1 mg/$2,157
LAMP2 / CD107b Protein - Recombinant Lysosomal Associated Membrane Protein 2 By SDS-PAGE
Select
E. coli
His-GST
47.0 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
LAMP2 / CD107b Protein - Purified recombinant protein LAMP2 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
42 kDa
20 µg/$1,107
LAMP2 / CD107b Protein - Purified recombinant protein LAMP2 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
42 kDa
20 µg/$1,107
LAMP2 / CD107b Protein - Purified recombinant protein LAMP2 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
42.2 kDa
20 µg/$1,107
LAMP2 / CD107b Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
Select
E. coli
His
19.6 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
Select
E. coli
His
20.5 kDa
10 µg/$283; 50 µg/$452; 100 µg/$725; 200 µg/$905; 1 mg/$2,020; 500 µg/$1,558; 5 mg/$3,165; 2 mg/$2,209
LAMP2 / CD107b Protein - Recombinant Lysosomal Associated Membrane Protein 2 By SDS-PAGE
Select
E. coli
His-GST
45.4 kDa
10 µg/$284; 50 µg/$462; 100 µg/$737; 200 µg/$922; 1 mg/$2,042; 500 µg/$1,577; 5 mg/$3,221; 2 mg/$2,231
Select
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
33.9 kDa
10 µg/$269; 50 µg/$368
Select
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
40.6 kDa
100 µg/$721
LAMP2 / CD107b Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
44.96 kDa
100 µg/$494
LAMP2 / CD107b Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
44.96 kDa
20 µg/$150
Viewing 1-13 of 13 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).