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LAGE3
L antigen family, member 3
Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. LAGE3 functions as a dimerization module for the complex.
| Gene Name: | L antigen family, member 3 |
| Synonyms: | LAGE3, CVG5, DXS9879E, DXS9951E, ESO3, L antigen family, member 3, L antigen family member 3, Protein ESO-3, ITBA2, Protein ITBA2 |
| Target Sequences: | NM_006014 NP_006005.2 Q14657 |
Publications (1)
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