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KSR2

kinase suppressor of Ras 2

Location-regulated scaffold connecting MEK to RAF. Has very low protein kinase activity and can phosphorylate MAP2K1 at several Ser and Thr residues with very low efficiency (in vitro). Interaction with BRAF enhances KSR2-mediated phosphorylation of MAP2K1 (in vitro). Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling. Acts as a negative regulator of MAP3K3-mediated activation of ERK, JNK and NF-kappa-B pathways, inhibiting MAP3K3-mediated interleukin-8 production.

Gene Name: kinase suppressor of Ras 2
Family/Subfamily: Protein Kinase , Raf
Synonyms: KSR2, Kinase suppressor of ras 2, HKSR2
Target Sequences: SK605D SK605P Q6VAB6

☰ Filters
Products
Antibodies (34)
Primary (34)
KSR2 (34)
Human (34)
Mouse (11)
Rat (2)
IHC (11)
IHC-P (3)
WB (30)
Flo (7)
ELISA (21)
ICC (2)
IF (13)
IP (1)
Peptide-ELISA (2)
rabbit (27)
mouse (7)
Product Group
IHCPlus (1)
IgG (23)
IgG1,k (6)
monoclonal mc (6)
polyclonal pc (28)
APC Conjugated (3)
Azide-free (2)
Biotin Conjugated (4)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (3)
Unconjugated (16)
aa603-638 (7)
aa808-836 (7)
640-720 aa, Internal (1)
Ile694 (1)
aa411-500 (1)
aa671-720 (1)
No (34)
KSR2 Antibody - Immunohistochemical analysis of KSR2 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
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KSR2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ICC, IF, IHC, IP, WB
Unconjugated
30 µl/$255; 100 µl/$299; 200 µl/$351
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KSR2 Rabbit anti-Human Polyclonal (640-720 aa, Internal) Antibody
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
KSR2 Antibody - KSR2 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human brain tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
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KSR2 Rabbit anti-Human Polyclonal (aa603-638) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
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KSR2 Rabbit anti-Human Polyclonal (aa603-638) Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
200 µl/$734
Select
KSR2 Rabbit anti-Human Polyclonal (aa603-638) (Biotin) Antibody
Human
ELISA, Flo, IHC, WB
Biotin Conjugated
200 µl/$952
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KSR2 Rabbit anti-Human Polyclonal (aa603-638) (FITC) Antibody
Human
ELISA, Flo, IHC, WB
FITC Conjugated
200 µl/$952
Select
KSR2 Rabbit anti-Human Polyclonal (aa603-638) (PE) Antibody
Human
ELISA, Flo, IHC, WB
PE Conjugated
200 µl/$952
Select
KSR2 Rabbit anti-Human Polyclonal (aa603-638) (Azide-free) (HRP) Antibody
Human
ELISA, Flo, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
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KSR2 Rabbit anti-Human Polyclonal (aa603-638) (APC) Antibody
Human
ELISA, Flo, IHC, WB
APC Conjugated
200 µl/$952
KSR2 Antibody - Immunohistochemistry image at a dilution of 1:100 and staining in paraffin-embedded human testis tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0) . Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4 °C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
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KSR2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
Select
KSR2 Mouse anti-Human Monoclonal (aa411-500) Antibody
Human
ELISA, IF, WB
Unconjugated
100 µg/$705
Select
KSR2 Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA, IF, WB
Biotin Conjugated
100 µl/$904
Select
KSR2 Mouse anti-Human Monoclonal (FITC) Antibody
Human
ELISA, IF, WB
FITC Conjugated
100 µl/$904
Select
KSR2 Mouse anti-Human Monoclonal (PE) Antibody
Human
ELISA, IF, WB
PE Conjugated
100 µl/$904
Select
KSR2 Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA, IF, WB
APC Conjugated
100 µl/$904
KSR2 Antibody - Western blot of 293 cell lysate using KSR2 Antibody
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KSR2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ICC, IF, WB
Unconjugated
50 µg/$305; 100 µg/$357
KSR2 Antibody - Staining 293 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody, diluted at 1/600, was used as secondary antibody.
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KSR2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
KSR2 Antibody - Peptide - + Immunofluorescence analysis of HeLa cells, using KSR2 antibody.
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KSR2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, WB
Unconjugated
100 µg/$357
KSR2 Antibody - Immunofluorescence analysis of HeLa cells, using KSR2 Antibody. The picture on the right is blocked with the synthesized peptide.
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KSR2 Rabbit anti-Human Polyclonal (aa671-720) Antibody
Mouse, Human
IF, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
Select
KSR2 Rabbit anti-Mouse Polyclonal (aa808-836) Antibody
Mouse, Human
ELISA, WB
Unconjugated
200 µl/$734
Select
KSR2 Rabbit anti-Mouse Polyclonal (aa808-836) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
KSR2 Rabbit anti-Mouse Polyclonal (aa808-836) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
KSR2 Rabbit anti-Mouse Polyclonal (aa808-836) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
KSR2 Rabbit anti-Mouse Polyclonal (aa808-836) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
KSR2 Rabbit anti-Mouse Polyclonal (aa808-836) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
Viewing 26-34 of 34 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).