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In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
Gene Name: | keratin associated protein 1-3 |
Synonyms: | KRTAP1-3, B2B, KAP1.2, KAP1.8, KAP1.8A, Keratin associated protein 1-3, Keratin associated protein 1.6, Keratin-associated protein 1.9, KAP1.3, KRATP1.9, KRTAP1.3, KAP1.6, KAP1.9, KRTAP1.8, KAP1.8B, Keratin-associated protein 1-3, Keratin-associated protein 1.8 |
Target Sequences: | NM_030966 NP_112228.1 Q8IUG1 |
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