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KRT83 / Keratin 83 / KRTHB3

keratin 83

The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB1 and KRTHB6, is found primarily in the hair cortex.

Gene Name: keratin 83
Family/Subfamily: Keratin , not assigned-Keratin
Synonyms: KRT83, Hard keratin, type II, 3, HB3, Hair keratin K2.10, K83, Keratin 83, Keratin, hair, basic, 3, Keratin, type II cuticular Hb3, HHb3, Keratin-83, KRTHB3, Type-II keratin Kb23, Hb-3, Type II hair keratin Hb3
Target Sequences: X99141 CAA67578.1 P78385

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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).