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KRT6B / CK6B / Cytokeratin 6B

keratin 6B

The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified; the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. Mutations in these genes have been associated with pachyonychia congenita. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.

Gene Name: keratin 6B
Family/Subfamily: Keratin , not assigned-Keratin
Synonyms: KRT6B, CK6B, Cytokeratin-6B, CK-6B, Cytokeratin 6B, K6B, Keratin 6B, K6b keratin, PC2, Type-II keratin Kb10, Keratin 6 isoform k6b, Keratin-6B, KRTL1
Target Sequences: NM_005555 NP_005546.2

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Proteins (4)
Over-Expression Lysate (2)
Recombinant (2)
KRT6B / CK6B / Cytokeratin 6B (4)
No (4)
6His, N-terminus (1)
GST (1)
Myc-DDK (Flag) (2)
Human (3)
293T Cells (1)
E. coli (1)
HEK 293 Cells (1)
Wheat Germ Extract (1)
Purified (1)
KRT6B / CK6B / Cytokeratin 6B Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
59.9 kDa
20 µg/$150
KRT6B / CK6B / Cytokeratin 6B Protein
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E. coli
6His, N-terminus
62.2 kDa
10 µg/$265; 50 µg/$315; 100 µg/$365; 250 µg/$518
KRT6B / CK6B / Cytokeratin 6B Protein - 12.5% SDS-PAGE of human KRT6B stained with Coomassie Blue
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Wheat Germ Extract
GST
87.78 kDa
10 µg/$479; 25 µg/$670
KRT6B / CK6B / Cytokeratin 6B Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
59.9 kDa
100 µg/$494
Viewing 1-4 of 4 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).