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KRT4 / CK4 / Cytokeratin 4

keratin 4

The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in differentiated layers of the mucosal and esophageal epithelia with family member KRT13. Mutations in these genes have been associated with White Sponge Nevus, characterized by oral, esophageal, and anal leukoplakia. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.

Gene Name: keratin 4
Family/Subfamily: Keratin , not assigned-Keratin
Synonyms: KRT4, CK-4, CK4, Cytokeratin 4, Cytokeratin-4, K4, Keratin 4, Type-II keratin Kb4, CYK4, Keratin-4
Target Sequences: X07695 CAA30534.1 P19013

Publications (1)

1
A case of primary combined neuroendocrine carcinoma with squamous cell carcinoma in the upper gingiva. Mochizuki Y, Omura K, Sakamoto K, Nakanishi S, Satoh K, Marukawa E, Yamaguchi A. Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics. 2010 109:e34-9. (IHC) [PubMed:20303044]

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Proteins (8)
Over-Expression Lysate (2)
Recombinant (6)
KRT4 / CK4 / Cytokeratin 4 (8)
No (8)
GST (1)
GST, N-terminus (1)
His (1)
His-S (1)
His-SUMO (1)
His-T7 (1)
Myc-DDK (Flag) (2)
Human (6)
Rat (1)
293T Cells (1)
E. coli (3)
HEK 293 Cells (1)
Wheat Germ Extract (2)
Yeast (1)
Purified (1)
KRT4 / CK4 / Cytokeratin 4 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
63.7 kDa
20 µg/$200
KRT4 / CK4 / Cytokeratin 4 Protein
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Yeast
His
59.2 kD
500 µg/$1,000; 100 µg/$436; 20 µg/$326
KRT4 / CK4 / Cytokeratin 4 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
63.7 kDa
100 µg/$607
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E. coli
His-SUMO
73.2 kD
1 mg/$1,152; 100 µg/$400; 20 µg/$307
KRT4 / CK4 / Cytokeratin 4 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$461; 25 µg/$611
KRT4 / CK4 / Cytokeratin 4 Protein - 12.5% SDS-PAGE of human KRT4 stained with Coomassie Blue
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Wheat Germ Extract
GST
84.48 kDa
10 µg/$461; 25 µg/$611
KRT4 / CK4 / Cytokeratin 4 Protein - Recombinant Keratin 4 By SDS-PAGE
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E. coli
His-T7
39.2 kDa
10 µg/$268; 50 µg/$403; 100 µg/$643; 200 µg/$803; 1 mg/$1,814
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E. coli
His-S
21.7 kDa
10 µg/$275; 50 µg/$441; 100 µg/$703; 200 µg/$879; 1 mg/$1,946
Viewing 1-8 of 8 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).