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KRT18 / CK18 / Cytokeratin 18

keratin 18

KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis.

Gene Name: keratin 18
Family/Subfamily: Keratin , not assigned-Keratin
Synonyms: KRT18, CK-18, Cytokeratin 18, Cytokeratin-18, K18, Keratin 18, CYK18, Keratin-18
Target Sequences: NM_000224 NP_000215.1 P05783

Publications (2)

1
Inhibition of peroxisome proliferator-activated receptor gamma increases estrogen receptor-dependent tumor specification. Yin Y, Yuan H, Zeng X, Kopelovich L, Glazer RI. Cancer research. 2009 69:687-94. (IHC) [PubMed:19147585]
2
Haploinsufficiency of Def activates p53-dependent TGF beta signalling and causes scar formation after partial hepatectomy. Zhu Z, Chen J, Xiong JW, Peng J. PloS one. 2014 9:e96576. [Full Text Article] [PubMed:24801718] [PMC:PMC4011785] Related Antibodies: LS-C22655.

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Products
Proteins (16)
Over-Expression Lysate (4)
Recombinant (12)
KRT18 / CK18 / Cytokeratin 18 (16)
No (16)
6His, N-terminus (3)
GST (2)
His, N-Terminal (3)
His, N-terminus (2)
His-T7 (2)
Myc-DDK (Flag) (4)
Human (10)
Mouse (2)
Pig (1)
Rat (1)
293T Cells (2)
E. coli (10)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (4)
KRT18 / CK18 / Cytokeratin 18 Protein - 12.5% SDS-PAGE of human KRT18 stained with Coomassie Blue
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Wheat Germ Extract
GST
72.82 kDa
10 µg/$479; 25 µg/$670
KRT18 / CK18 / Cytokeratin 18 Protein - Recombinant Keratin 18 By SDS-PAGE
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E. coli
His, N-Terminal
24.8 kDa Observed: 29 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 5 mg/$2,941; 2 mg/$2,119
KRT18 / CK18 / Cytokeratin 18 Protein - Recombinant Keratin 18 By SDS-PAGE
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E. coli
His, N-Terminal
49.1 kDa
10 µg/$284; 50 µg/$462; 100 µg/$737; 200 µg/$922; 1 mg/$2,042; 500 µg/$1,577; 5 mg/$3,221; 2 mg/$2,231
KRT18 / CK18 / Cytokeratin 18 Protein - SDS-PAGE under reducing conditions and visualized by Coomassie blue staining
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E. coli
6His, N-terminus
49 kDa
10 µg/$265; 50 µg/$315; 100 µg/$365; 500 µg/$949
KRT18 / CK18 / Cytokeratin 18 Protein - Recombinant Keratin 18 By SDS-PAGE
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E. coli
His-T7
39.4 kDa
10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284
KRT18 / CK18 / Cytokeratin 18 Protein - Recombinant Mouse KRT18 Protein (His Tag)-Elabscience
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E. coli
His, N-terminus
25.48 kDa
20 µg/$270; 100 µg/$390
KRT18 / CK18 / Cytokeratin 18 Protein
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E. coli
His, N-Terminal
47.9 kDa
50 µg/$419
KRT18 / CK18 / Cytokeratin 18 Protein - Recombinant Human KRT18 Protein (His Tag)-Elabscience
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E. coli
His, N-terminus
18.06 kDa
20 µg/$270; 100 µg/$390
KRT18 / CK18 / Cytokeratin 18 Protein - 12.5% SDS-PAGE of human KRT18 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
72.82 kDa
10 µg/$479; 25 µg/$670
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E. coli
6His, N-terminus
1 mg/$1,355; 100 µg/$420; 20 µg/$323
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E. coli
6His, N-terminus
1 mg/$1,355; 100 µg/$420; 20 µg/$323
KRT18 / CK18 / Cytokeratin 18 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
47.9 kDa
20 µg/$150
KRT18 / CK18 / Cytokeratin 18 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
47.9 kDa
20 µg/$150
KRT18 / CK18 / Cytokeratin 18 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
47.9 kDa
100 µg/$494
KRT18 / CK18 / Cytokeratin 18 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
47.9 kDa
100 µg/$494
KRT18 / CK18 / Cytokeratin 18 Protein - Recombinant Keratin 18 By SDS-PAGE
Select
E. coli
His-T7
21.9 kDa
50 µg/$462; 10 µg/$284; 200 µg/$922; 100 µg/$737; 1 mg/$2,042; 500 µg/$1,577; 5 mg/$3,221; 2 mg/$2,231
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).