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KRT1 / CK1 / Cytokeratin 1
keratin 1
KRT1 / CK1 / Cytokeratin 1 is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
| Gene Name: | keratin 1 |
| Family/Subfamily: | Keratin , not assigned-Keratin |
| Synonyms: | KRT1, 67 kDa cytokeratin, CK-1, CK1, Cytokeratin 1, Cytokeratin-1, Epidermolytic hyperkeratosis 1, EHK, EHK1, Hair alpha protein, EPPK, NEPPK, K1, Keratin-1, KRTA, Type-II keratin Kb1, Type II keratin, Keratin 1, KRT1A |
| Target Sequences: | NM_006121 NP_006112.3 P04264 |
Publications (5)
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