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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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KRT1 / CK1 / Cytokeratin 1

keratin 1

KRT1 / CK1 / Cytokeratin 1 is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.

Gene Name: keratin 1
Family/Subfamily: Keratin , not assigned-Keratin
Synonyms: KRT1, 67 kDa cytokeratin, CK-1, CK1, Cytokeratin 1, Cytokeratin-1, Epidermolytic hyperkeratosis 1, EHK, EHK1, Hair alpha protein, EPPK, NEPPK, K1, Keratin-1, KRTA, Type-II keratin Kb1, Type II keratin, Keratin 1, KRT1A
Target Sequences: NM_006121 NP_006112.3 P04264

Publications (5)

1
Activated keratinocytes in the epidermis of hypertrophic scars. Machesney M, Tidman N, Waseem A, Kirby L, Leigh I. The American journal of pathology. 1998 152:1133-41. [PubMed:9588880] [PMC:PMC1858601]
2
Characterization and comparison of reconstructed skin models: morphological and immunohistochemical evaluation. Boelsma E, Gibbs S, Faller C, Ponec M. Acta dermato-venereologica. 80:82-8. [PubMed:10877124]
3
A human keratin 10 knockout causes recessive epidermolytic hyperkeratosis. Mller FB, Huber M, Kinaciyan T, Hausser I, Schaffrath C, Krieg T, Hohl D, Korge BP, Arin MJ. Human molecular genetics. 2006 15:1133-41. (ICC) [PubMed:16505000]
4
Modified plastic compression of collagen hydrogels provides an ideal matrix for clinically applicable skin substitutes. Braziulis E, Diezi M, Biedermann T, Pontiggia L, Schmucki M, Hartmann-Fritsch F, Luginbhl J, Schiestl C, Meuli M, Reichmann E. Tissue engineering. Part C, Methods. 2012 18:464-74. (ICC, IHC; Human) [PubMed:22195768]
5
Human amniotic fluid derived cells can competently substitute dermal fibroblasts in a tissue-engineered dermo-epidermal skin analog. Hartmann-Fritsch F, Hosper N, Luginbhl J, Biedermann T, Reichmann E, Meuli M. Pediatric surgery international. 2013 29:61-9. (ICC, IHC; Human) [PubMed:23138462]
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Filtered by: None
Target
KRT1 / CK1 / Cytokeratin 1 (54)
Reactivity
Human (37)
Mouse (23)
Rat (37)
Chimpanzee (3)
Gibbon (3)
Monkey (4)
Pig (8)
Application
IHC (16)
IHC-Fr (2)
IHC-P (10)
WB (49)
ELISA (7)
ICC (2)
IF (2)
IP (2)
Host
rabbit (47)
mouse (6)
guinea pig (1)
Isotype
IgG (15)
IgG1 (3)
IgG2a,k (2)
Clonality
monoclonal mc (6)
polyclonal pc (48)
Clone
2A7 (1)
34BetaB4 (1)
3C10F7, 3C10G5 (1)
3C10F7, 3C10G5, PMC01, 4D12B3,3C10F7C11 (1)
ABT-CK1 (1)
Format
APC (4)
APC Conjugated (4)
Biotin Conjugated (6)
Cy3 Conjugated (4)
Cy7 Conjugated (4)
FITC Conjugated (6)
HRP Conjugated (6)
PE Conjugated (4)
Unconjugated (20)
Epitope
aa189-497 (8)
aa350-488 (8)
aa487-644 (8)
aa489-625 (8)
C-Terminus (4)
Internal (2)
aa223-257 (1)
Publications
No (54)
Showing 1-25 of 54 results

IHC-plus™ KRT1 / CK1 / Cytokeratin 1 Antibody (Internal) LS-B7799
Rabbit Polyclonal (IgG) to Human KRT1 / CK1 / Cytokeratin 1
Mouse, Rat, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50µl  $425.00
Anti-Cytokeratin 1 / Keratin 1 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Western blot Image

IHC-plus™ KRT1 / CK1 / Cytokeratin 1 Antibody (C-Terminus) LS-B3989
Rabbit Polyclonal (IgG) to Human KRT1 / CK1 / Cytokeratin 1
Human, Monkey
IHC, IHC-P, WB
Unconjugated
100µl  $485.00
Anti-KRT1 / Cytokeratin 1 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of 293T cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

KRT1 / CK1 / Cytokeratin 1 Antibody (C-Terminus, HRP) LS-C443481
Rabbit Polyclonal (IgG) to Human KRT1 / CK1 / Cytokeratin 1
Human, Monkey, Chimpanzee, Gibbon
IHC, IHC-P, WB
HRP Conjugated
100µl 0.65mg/ml  $405.00
Anti-KRT1 / Cytokeratin 1 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of 293T cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

KRT1 / CK1 / Cytokeratin 1 Antibody (C-Terminus, Biotin) LS-C443479
Rabbit Polyclonal (IgG) to Human KRT1 / CK1 / Cytokeratin 1
Human, Monkey, Chimpanzee, Gibbon
IHC, IHC-P, WB
Biotin Conjugated
100µl 1mg/ml  $405.00
Anti-KRT1 / Cytokeratin 1 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of 293T cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

KRT1 / CK1 / Cytokeratin 1 Antibody (C-Terminus, FITC) LS-C443480
Rabbit Polyclonal (IgG) to Human KRT1 / CK1 / Cytokeratin 1
Human, Monkey, Chimpanzee, Gibbon
IHC, IHC-P, WB
FITC Conjugated
100µl 1mg/ml  $405.00
Anti-KRT1 / Cytokeratin 1 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of 293T cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

KRT1 / CK1 / Cytokeratin 1 Antibody (Internal) LS-C137105
Rabbit Polyclonal (IgG) to Human KRT1 / CK1 / Cytokeratin 1
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100µl  $275.00
Western blot Image

KRT1 / CK1 / Cytokeratin 1 Antibody (clone 34BetaB4) LS-C343835
Mouse Monoclonal [clone 34BetaB4] (IgG1) to Human KRT1 / CK1 / Cytokeratin 1
Human
IHC, IHC-P, WB
Unconjugated
500µl  $345.00
Immunohistochemistry of human skin tissue using Cytokeratin 1 (human)monoclonal antibody (34 beta B4) at a dilution of 1:20.

KRT1 / CK1 / Cytokeratin 1 Antibody (clone 3C10F7, 3C10G5) LS-C47183
Mouse Monoclonal [clone 3C10F7, 3C10G5] (IgG1) to Human KRT1 / CK1 / Cytokeratin 1
ELISA, IHC, IHC-Fr, WB
Unconjugated
100µl 1mg/ml  $315.00
IHC analysis of FFPE liver tissue, colon carcinoma, lung carcinoma, and esophagus using DAB staining
Western blot analysis of truncated CK1 recombinant protein

KRT1 / CK1 / Cytokeratin 1 Antibody LS-C673185
Rabbit Polyclonal (IgG) to Human KRT1 / CK1 / Cytokeratin 1
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50µg  $285.00; 100µg  $385.00
Immunohistochemistry image at a dilution of 1:400 and staining in paraffin-embedded human cervical cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0) . Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4 °C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Immunohistochemistry image at a dilution of 1:400 and staining in paraffin-embedded human liver cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0) . Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4 °C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

KRT1 / CK1 / Cytokeratin 1 Antibody LS-C754815
Rabbit Polyclonal (IgG) to Human KRT1 / CK1 / Cytokeratin 1
Human
ELISA, IF, IHC, IP, WB
Unconjugated
100µg  $355.00

KRT1 / CK1 / Cytokeratin 1 Antibody LS-C64250
Mouse Monoclonal (IgG2a,k) to Human KRT1 / CK1 / Cytokeratin 1
Human
ICC, IHC, IHC-Fr, IHC-P, WB
Unconjugated
100µg  $530.00

KRT1 / CK1 / Cytokeratin 1 Antibody (aa223-257) LS-C407868
Rabbit Polyclonal to Mouse KRT1 / CK1 / Cytokeratin 1
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100µg  $355.00
Cytokeratin 1 antibody IHC-paraffin. IHC(P): Rat Lung Tissue.
Cytokeratin 1 antibody IHC-paraffin. IHC(P): Human Esophagus Squama Cancer Tissue.

KRT1 / CK1 / Cytokeratin 1 Antibody LS-C490329
Rabbit Polyclonal (IgG) to Human KRT1 / CK1 / Cytokeratin 1
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100µg  $435.00
Immunohistochemistry - Paraffin Image
Immunohistochemistry - Paraffin Image

KRT1 / CK1 / Cytokeratin 1 Antibody (aa487-644) LS-C294985
Rabbit Polyclonal to Human KRT1 / CK1 / Cytokeratin 1
Mouse, Rat, Pig, Human
ICC, IP, WB
Unconjugated
20µl 0.5mg/ml  $195.00; 100µl 0.5mg/ml  $245.00; 200µl 0.5mg/ml  $285.00; 1ml 0.5mg/ml  $475.00
Western blot of recombinant KRT1 / CK1 / Cytokeratin 1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western Blot; Sample: Recombinant KRT1, Human.

KRT1 / CK1 / Cytokeratin 1 Antibody (clone 3C10F7, 3C10G5, PMC01, 4D12B3,3C10F7C11) LS-C758500
Mouse Monoclonal [clone 3C10F7, 3C10G5, PMC01, 4D12B3,3C10F7C11] (IgG1) to Human KRT1 / CK1 / Cytokeratin 1
Human
IHC, WB
Unconjugated
100µl  $405.00
CK1 alpha Antibody in Immunohistochemistry (IHC)
CK1 alpha Antibody in Western Blot (WB)

KRT1 / CK1 / Cytokeratin 1 Antibody (clone 2A7) LS-C197586
Mouse Monoclonal [clone 2A7] (IgG2a,k) to Human KRT1 / CK1 / Cytokeratin 1
Human
ELISA, WB
Unconjugated
100µg  $365.00
Detection limit for recombinant GST tagged KRT1 is 0.3 ng/ml as a capture antibody.

KRT1 / CK1 / Cytokeratin 1 Antibody LS-C193763
Guinea pig Polyclonal to Human KRT1 / CK1 / Cytokeratin 1
Mouse, Human
IHC, WB
Unconjugated
100µl  $635.00

KRT1 / CK1 / Cytokeratin 1 Antibody (aa189-497) LS-C294988
Rabbit Polyclonal to Mouse KRT1 / CK1 / Cytokeratin 1
Mouse, Rat
WB
Unconjugated
20µl 0.5mg/ml  $195.00; 100µl 0.5mg/ml  $255.00; 200µl 0.5mg/ml  $285.00; 1ml 0.5mg/ml  $485.00
Western blot of recombinant KRT1 / CK1 / Cytokeratin 1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western Blot; Sample: Recombinant protein.

KRT1 / CK1 / Cytokeratin 1 Antibody (aa189-497, HRP) LS-C707473
Rabbit Polyclonal to Mouse KRT1 / CK1 / Cytokeratin 1
Mouse, Rat
WB
HRP Conjugated
100µl 0.5mg/ml  $275.00; 200µl 0.5mg/ml  $325.00; 1ml 0.5mg/ml  $635.00
Western blot of recombinant KRT1 / CK1 / Cytokeratin 1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western Blot; Sample: Recombinant protein.

KRT1 / CK1 / Cytokeratin 1 Antibody (aa189-497, PE) LS-C721536
Rabbit Polyclonal to Mouse KRT1 / CK1 / Cytokeratin 1
Mouse, Rat
WB
PE Conjugated
100µl 0.1mg/ml  $245.00; 200µl 0.1mg/ml  $275.00; 1ml 0.1mg/ml  $455.00
Western blot of recombinant KRT1 / CK1 / Cytokeratin 1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western Blot; Sample: Recombinant protein.

KRT1 / CK1 / Cytokeratin 1 Antibody (aa189-497, APC) LS-C715655
Rabbit Polyclonal to Mouse KRT1 / CK1 / Cytokeratin 1
Mouse, Rat
WB
APC Conjugated
100µl 0.1mg/ml  $265.00; 200µl 0.1mg/ml  $305.00; 1ml 0.1mg/ml  $545.00
Western blot of recombinant KRT1 / CK1 / Cytokeratin 1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western Blot; Sample: Recombinant protein.

KRT1 / CK1 / Cytokeratin 1 Antibody (aa189-497, Cy3) LS-C698452
Rabbit Polyclonal to Mouse KRT1 / CK1 / Cytokeratin 1
Mouse, Rat
WB
Cy3 Conjugated
100µl 0.1mg/ml  $345.00; 200µl 0.1mg/ml  $415.00; 1ml 0.1mg/ml  $965.00
Western blot of recombinant KRT1 / CK1 / Cytokeratin 1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western Blot; Sample: Recombinant protein.

KRT1 / CK1 / Cytokeratin 1 Antibody (aa189-497, APC, Cy7) LS-C730541
Rabbit Polyclonal to Mouse KRT1 / CK1 / Cytokeratin 1
Mouse, Rat
WB
APC, Cy7 Conjugated
100µl 0.1mg/ml  $365.00; 200µl 0.1mg/ml  $455.00; 1ml 0.1mg/ml  $1,080.00
Western blot of recombinant KRT1 / CK1 / Cytokeratin 1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western Blot; Sample: Recombinant protein.

KRT1 / CK1 / Cytokeratin 1 Antibody LS-C804155
Rabbit Polyclonal (IgG) to Human KRT1 / CK1 / Cytokeratin 1
Mouse, Human
ELISA, WB
Unconjugated
100µl 1mg/ml  $325.00; 200µl 1mg/ml  $375.00
Western blot Image

KRT1 / CK1 / Cytokeratin 1 Antibody (clone ABT-CK1) LS-C744485
Mouse Monoclonal [clone ABT-CK1] (IgG) to Human KRT1 / CK1 / Cytokeratin 1
Human
IHC
Unconjugated
50µl 1mg/ml  $265.00; 100µl 1mg/ml  $325.00
Skin 1
Skin 2
Showing 1-25 of 54 results

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For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).