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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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KMT2D / MLL2

lysine (K)-specific methyltransferase 2D

Histone methyltransferase. Methylates 'Lys-4' of histone H3 (H3K4me). H3K4me represents a specific tag for epigenetic transcriptional activation. Acts as a coactivator for estrogen receptor by being recruited by ESR1, thereby activating transcription.

Gene Name: lysine (K)-specific methyltransferase 2D
Synonyms: KMT2D, AAD10, ALL1-related protein, KABUK1, KMS, Lysine N-methyltransferase 2D, MLL2, Kabuki make-up syndrome, ALR, CAGL114, KMT2B, Lysine N-methyltransferase 2B, TNRC21
Target Sequences: NM_003482 NP_003473.3 O14686

Publications (1)

1
MLL histone methylases regulate expression of HDLR-SR-B1 in presence of estrogen and control plasma cholesterol in vivo. Ansari KI, Kasiri S, Hussain I, Bobzean SA, Perrotti LI, Mandal SS. Molecular and cellular endocrinology. 2013 27:92-105. (ELISA; Human) [Full Text Article] [PubMed:23192982]

Filtered By: None
Target
KMT2D / MLL2 (9)
Reactivity
Human (9)
Application
IHC (2)
IHC-P (2)
WB (1)
ELISA (8)
Peptide-ELISA (1)
Host
rabbit (7)
mouse (1)
goat (1)
Isotype
IgG (7)
IgG2a,k (1)
Clonality
monoclonal mc (1)
polyclonal pc (8)
Clone
2E1 (1)
Format
AP Conjugated (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
PE Conjugated (1)
Unconjugated (3)
Epitope
C-Terminus (7)
aa2-14 (1)
Publications
No (9)
Showing 1-9 of 9 results

KMT2D / MLL2 Antibody (clone 2E1) IHC-plus™ LS-B11763
Mouse Monoclonal [clone 2E1] (IgG2a,k) to Human KMT2D / MLL2
Human
ELISA IHC IHC-P WB
Unconjugated
50µg 0.5mg/ml  $485.00
Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)

KMT2D / MLL2 Antibody (aa2-14) IHC-plus™ LS-B8291
Goat Polyclonal to Human KMT2D / MLL2
Human
IHC IHC-P Peptide-ELISA
Unconjugated
50µg 0.5mg/ml  $425.00
Anti-MLL2 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 3.75 ug/ml.
Anti-MLL2 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 3.75 ug/ml.

KMT2D / MLL2 Antibody (C-Terminus) LS-C329835
Rabbit Polyclonal (IgG) to Human KMT2D / MLL2
Human
ELISA
Unconjugated
200µl  $530.00

KMT2D / MLL2 Antibody (C-Terminus, Biotin) LS-C215797
Rabbit Polyclonal (IgG) to Human KMT2D / MLL2
Human
ELISA
Biotin Conjugated
200µl  $680.00

KMT2D / MLL2 Antibody (C-Terminus, FITC) LS-C215799
Rabbit Polyclonal (IgG) to Human KMT2D / MLL2
Human
ELISA
FITC Conjugated
200µl  $680.00

KMT2D / MLL2 Antibody (C-Terminus, AP) LS-C215796
Rabbit Polyclonal (IgG) to Human KMT2D / MLL2
Human
ELISA
AP Conjugated
200µl  $680.00

KMT2D / MLL2 Antibody (C-Terminus, APC) LS-C215798
Rabbit Polyclonal (IgG) to Human KMT2D / MLL2
Human
ELISA
APC Conjugated
200µl  $680.00

KMT2D / MLL2 Antibody (C-Terminus, PE) LS-C215801
Rabbit Polyclonal (IgG) to Human KMT2D / MLL2
Human
ELISA
PE Conjugated
200µl  $680.00

KMT2D / MLL2 Antibody (C-Terminus, Azide-free, HRP) LS-C215800
Rabbit Polyclonal (IgG) to Human KMT2D / MLL2
Human
ELISA
HRP Conjugated, Azide-free
200µl  $680.00
Showing 1-9 of 9 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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