KLKB1 / Plasma Kallikrein

kallikrein B, plasma (Fletcher factor) 1

Plasma prekallikrein is a glycoprotein that participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation. It is synthesized in the liver and secreted into the blood as a single polypeptide chain. Plasma prekallikrein is converted to plasma kallikrein by factor XIIa by the cleavage of an internal Arg-Ile bond. Plasma kallikrein therefore is composed of a heavy chain and a light chain held together by a disulphide bond. The heavy chain originates from the amino-terminal end of the zymogen and contains 4 tandem repeats of 90 or 91 amino acids. Each repeat harbors a novel structure called the apple domain. The heavy chain is required for the surface-dependent pro-coagulant activity of plasma kallikrein. The light chain contains the active site or catalytic domain of the enzyme and is homologous to the trypsin family of serine proteases. Plasma prekallikrein deficiency causes a prolonged activated partial thromboplastin time in patients.

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Products

Proteins (8)

Type

Over-Expression Lysate (2)

Recombinant (6)

Target

KLKB1 / Plasma Kallikrein (8)

Publications

No (8)

Tag

6His, C-terminus (2)

6His, N-terminus (3)

Myc-DDK (Flag) (3)

Species

Human (5)

Rat (2)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (2)

Human Cells (1)

Mammalian Cells (1)

Yeast (2)

Purification

Purified (1)

Low Endotoxin Level

Low endotoxin level (2)

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Rat KLKB1 / Plasma Kallikrein Protein (Recombinant 6His, N-terminus) (aa391-638) - LS-G22996

Source:

Yeast

Tag:

6His, N-terminus

Molecular Weight:

29.8 kD

Price:

100 µg/$499; 20 µg/$364; 1 mg/$1,683

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Rat KLKB1 / Plasma Kallikrein Protein (Recombinant 6His, N-terminus) (aa391-638) - LS-G20900

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

31.9 kD

Price:

1 mg/$1,679; 100 µg/$500; 20 µg/$364

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Human KLKB1 / Plasma Kallikrein Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78089

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

71.37 kDa

Price:

20 µg/$215

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Human KLKB1 / Plasma Kallikrein Protein (Recombinant 6His, N-terminus) (aa20-390) - LS-G57212

Source:

Yeast

Tag:

6His, N-terminus

Price:

100 µg/$446; 20 µg/$336; 1 mg/$1,460

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Human KLKB1 / Plasma Kallikrein Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66602

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

41.3 kDa

Price:

20 µg/$1,107

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KLKB1 / Plasma Kallikrein Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99203

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

71.37 kDa

Price:

100 µg/$710

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Human KLKB1 / Plasma Kallikrein Protein (Recombinant 6His, C-terminus) (Gly20-Ala638) - LS-G39982

Source:

Human Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

70.2kD

Price:

10 µg/$288; 50 µg/$442; 500 µg/$1,585; 1 mg/$2,157

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Human KLKB1 / Plasma Kallikrein Protein (Recombinant 6His, C-terminus) (Gly20-Ala638) - LS-G139668

Source:

Mammalian Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

70.2 kDa

Price:

10 µg/$376; 50 µg/$526

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