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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Cell Cycle Pathways
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KLKB1 / Plasma Kallikrein

kallikrein B, plasma (Fletcher factor) 1

Plasma prekallikrein is a glycoprotein that participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation. It is synthesized in the liver and secreted into the blood as a single polypeptide chain. Plasma prekallikrein is converted to plasma kallikrein by factor XIIa by the cleavage of an internal Arg-Ile bond. Plasma kallikrein therefore is composed of a heavy chain and a light chain held together by a disulphide bond. The heavy chain originates from the amino-terminal end of the zymogen and contains 4 tandem repeats of 90 or 91 amino acids. Each repeat harbors a novel structure called the apple domain. The heavy chain is required for the surface-dependent pro-coagulant activity of plasma kallikrein. The light chain contains the active site or catalytic domain of the enzyme and is homologous to the trypsin family of serine proteases. Plasma prekallikrein deficiency causes a prolonged activated partial thromboplastin time in patients.

Gene Name: kallikrein B, plasma (Fletcher factor) 1
Family/Subfamily: Protease , Serine S1
Synonyms: KLKB1, Fletcher factor deficiency, Fletcher factor, Kininogenin, Plasma kallikrein, PKK deficiency, Plasma kallikrein heavy chain, PPK, Prekallikrein deficiency, Plasma kallikrein light chain, Plasma prekallikrein, Kallikrein 3
Target Sequences: NM_000892 NP_000883.2 P03952

Viewing 1-25 of 41 items
KLKB1 / Plasma Kallikrein Antibody - Anti-KLKB1 antibody IHC of human small intestine, vessels. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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Sheep Polyclonal (IgG) to Human KLKB1 / Plasma Kallikrein
Human
ELISA, IE, IHC, IHC-P
Unconjugated
50µg   1mg/ml   $425.00
KLKB1 / Plasma Kallikrein Antibody - Immunohistochemistry of paraffin-embedded rat kidney tissue.
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Rabbit Polyclonal (IgG) to Human KLKB1 / Plasma Kallikrein
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
50µl   $235.00; 100µl   $315.00; 200µl   0.69mg/ml   $425.00
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Mouse Monoclonal [clone 13G11] (IgG1) to Human KLKB1 / Plasma Kallikrein
Human
ELISA, WB
Unconjugated
100µg   1.61mg/ml   $680.00; 200µg   $1,245.00
KLKB1 / Plasma Kallikrein Antibody - Western blot analyses of prekallikrein and its activation products in human plasma.
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Mouse Monoclonal [clone 13G11] (IgG1) to Human KLKB1 / Plasma Kallikrein
Human
ELISA, WB
Unconjugated
200µg   1.6mg/ml   $495.00
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Goat Polyclonal (IgG) to Human KLKB1 / Plasma Kallikrein
Human, Monkey
ELISA, IE
Unconjugated
1ml   $620.00
KLKB1 / Plasma Kallikrein Antibody - KLKB1 Antibody western blot of K562 cell line lysates (35 ug/lane). The KLKB1 antibody detected the KLKB1 protein (arrow).
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Rabbit Polyclonal to Human KLKB1 / Plasma Kallikrein
Human
WB
Unconjugated
400µl   $325.00
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Rabbit Polyclonal (IgG) to Rat KLKB1 / Plasma Kallikrein
Rat
ELISA
Unconjugated
50µg   5mg/ml   $285.00; 100µg   5mg/ml   $385.00
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Rabbit Polyclonal (IgG) to Rat KLKB1 / Plasma Kallikrein
Rat
ELISA
HRP Conjugated
50µg   0.42mg/ml   $285.00; 100µg   0.42mg/ml   $385.00
KLKB1 / Plasma Kallikrein Antibody - Western blot of Cleaved-Plasma Kallikrein HC (R390) antibody
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Rabbit Polyclonal (IgG) to Human KLKB1 / Plasma Kallikrein
Human
ELISA, IHC, WB
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $265.00; 200µl   1mg/ml   $335.00
KLKB1 / Plasma Kallikrein Antibody - Immunohistochemistry of paraffin-embedded human liver tissue using KLKB1 Antibody at dilution of 1:100
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Rabbit Polyclonal (IgG) to Human KLKB1 / Plasma Kallikrein
Human
ELISA, IHC
Unconjugated
50µg   5mg/ml   $245.00; 100µg   $385.00
Select
Rabbit Polyclonal (IgG) to Human KLKB1 / Plasma Kallikrein
Human
ELISA
HRP Conjugated
50µg   0.42mg/ml   $285.00; 100µg   0.42mg/ml   $385.00
KLKB1 / Plasma Kallikrein Antibody - KLKB1 antibody Western blot of Rat Brain lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Rabbit Polyclonal to Rat KLKB1 / Plasma Kallikrein
Rabbit, Dog, Bovine, Rat, Horse
WB
Unconjugated
100µl   0.5mg/ml   $365.00
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Rat Monoclonal (IgG1) to Mouse KLKB1 / Plasma Kallikrein
Mouse
ELISA, WB
Unconjugated
100µg   $680.00
Select
Rabbit Polyclonal to Human KLKB1 / Plasma Kallikrein
Mouse, Rat, Human
IF, WB
Unconjugated
100µl   $385.00
Select
Rabbit Polyclonal (IgG) to Human KLKB1 / Plasma Kallikrein
Human
ELISA, WB
Unconjugated
200µl   0.54mg/ml   $590.00
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Rabbit Polyclonal (IgG) to Human KLKB1 / Plasma Kallikrein
Human
ELISA, WB
HRP Conjugated, Azide-free
200µl   $740.00
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Rabbit Polyclonal (IgG) to Human KLKB1 / Plasma Kallikrein
Human
ELISA, WB
AP Conjugated
200µl   $740.00
KLKB1 / Plasma Kallikrein Antibody - Fetal liver cell lysate. Antibody concentration: 2.5 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Rabbit Polyclonal (IgG) to Human KLKB1 / Plasma Kallikrein
Dog, Pig, Horse, Human
WB
Unconjugated
100µl   0.5mg/ml   $325.00
KLKB1 / Plasma Kallikrein Antibody - Anti-KLKB1 / Plasma Kallikrein antibody IHC staining of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Rabbit Polyclonal (IgG) to Human KLKB1 / Plasma Kallikrein
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50µl   1mg/ml   $425.00
KLKB1 / Plasma Kallikrein Antibody - Western blot All Lanes:Plasma kallikrein antibody at 2ug/ml Lane 1:Hela whole cell lysate Lane 2:rat brain tissue Secondary Goat polyclonal to rabbit at 1/10000 dilution Predicted band size: 71kDa Observed band size: 71kDa
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Rabbit Polyclonal (IgG) to Rat KLKB1 / Plasma Kallikrein
Rat
ELISA, WB
Unconjugated
50µg   4.12mg/ml   $285.00; 100µg   $385.00
Select
Rabbit Polyclonal (IgG) to Rat KLKB1 / Plasma Kallikrein
Rat
ELISA
HRP Conjugated
50µg   0.42mg/ml   $245.00; 100µg   $385.00
KLKB1 / Plasma Kallikrein Antibody - Immunohistochemical analysis of Plasma Kallikrein HC staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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Rabbit Polyclonal to Human KLKB1 / Plasma Kallikrein
Human
IHC, IHC-P, WB
Unconjugated
100µl   1mg/ml   $275.00
KLKB1 / Plasma Kallikrein Antibody
Select
Rabbit Polyclonal (IgG) to Human KLKB1 / Plasma Kallikrein
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00
Select
Rabbit Polyclonal (IgG) to Human KLKB1 / Plasma Kallikrein
Mouse, Rat, Human
IHC, WB
Unconjugated
60µl   1mg/ml   $235.00; 120µl   1mg/ml   $295.00; 200µl   1mg/ml   $395.00
Select
Rabbit Polyclonal (IgG) to Human KLKB1 / Plasma Kallikrein
Human
IF
Unconjugated
50µl   $235.00; 100µl   $295.00; 200µl   $385.00

Viewing 1-25 of 41 items


If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).