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KLK4 / Kallikrein 4

kallikrein-related peptidase 4

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. In some tissues its expression is hormonally regulated. The expression pattern of a similar mouse protein in murine developing teeth supports a role for the protein in the degradation of enamel proteins. Several transcript variants encoding different proteins have been found for this gene.

Gene Name: kallikrein-related peptidase 4
Family/Subfamily: Protease , Serine S1
Synonyms: KLK4, AI2A1, ARM1, Androgen-regulated message 1, EMSP, EMSP1, Kallikrein-like protein 1, Kallikrein, Prostase, PRSS17, PSTS, Kallikrein 4, Kallikrein-4, Kallikrein-related peptidase 4, KLK-L1, Serine protease 17
Target Sequences: NM_004917 NP_004908.4 Q9Y5K2

Publications (1)

1
Full Spectrum of Postnatal Tooth Phenotypes in a Novel Irf6 Cleft Lip Model. Chu EY, Tamasas B, Fong H, Foster BL, LaCourse MR, Tran AB, Martin JF, Schutte BC, Somerman MJ, Cox TC. Journal of dental research. 2016 October;95:1265-73. (Human) [Full Text Article] [PubMed:27369589] [PMC:PMC5076757]

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KLK4 / Kallikrein 4 (2)
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KLK4 / Kallikrein 4 ELISA Kit
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Sandwich
96-Well Microplate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$764
KLK4 / Kallikrein 4 ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$818
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).