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KLK1 / Kallikrein 1

kallikrein 1

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. This protein is functionally conserved in its capacity to release the vasoactive peptide, Lys-bradykinin, from low molecular weight kininogen.

Gene Name: kallikrein 1
Family/Subfamily: Protease , Serine S1
Synonyms: KLK1, Glandular kallikrein 1, Kallikrein-1, KLKR, Kallikrein 1, Kallikrein serine protease 1, Tissue kallikrein
Target Sequences: NM_002257 NP_002248.1 P06870

Publications (1)

1
Unexpected kidney-restricted role for IL-17 receptor signaling in defense against systemic Candida albicans infection. Ramani K, Jawale CV, Verma AH, Coleman BM, Kolls JK, Biswas PS. JCI insight. 2018 May;3:pii: 98241. [Full Text Article] [PubMed:29720566] [PMC:PMC6012520] Related Antibodies: LS-C312857.

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).