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KLHL22

kelch-like family member 22

Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for chromosome alignment and localization of PLK1 at kinetochores. The BCR(KLHL22) ubiquitin ligase complex mediates monoubiquitination of PLK1, leading to PLK1 dissociation from phosphoreceptor proteins and subsequent removal from kinetochores, allowing silencing of the spindle assembly checkpoint (SAC) and chromosome segregation. Monoubiquitination of PLK1 does not lead to PLK1 degradation.

Gene Name: kelch-like family member 22
Synonyms: KLHL22, Kelch-like 22 (Drosophila), Kelch-like protein 22, KELCHL
Target Sequences: NM_032775 NP_116164.2 Q53GT1

☰ Filters
Products
Antibodies (19)
Primary (19)
KLHL22 (19)
Human (19)
Mouse (11)
Rat (3)
Bat (3)
Bovine (3)
Chimpanzee (3)
Dog (3)
Gibbon (3)
Horse (3)
Monkey (3)
Pig (3)
WB (19)
ELISA (13)
ICC (1)
IF (3)
rabbit (16)
mouse (3)
IgG (11)
IgG1 (3)
monoclonal mc (3)
polyclonal pc (16)
7B10 (2)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (1)
Unconjugated (8)
aa586-614 (7)
aa175-224 (4)
No (19)
KLHL22 Antibody - KLHL22 Antibody in Immunofluorescence (IF)
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KLHL22 Mouse anti-Human Monoclonal (7B10) Antibody
Mouse, Human
ICC, IF, WB
Unconjugated
100 µl/$541
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KLHL22 Mouse anti-Human Monoclonal Antibody
Human
ELISA, IF, WB
Unconjugated
50 µg/$332; 100 µg/$404; 200 µg/$505
KLHL22 Antibody - Immunofluorescence of U251 cells using KLHL22 mouse monoclonal antibody (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
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KLHL22 Mouse anti-Human Monoclonal (7B10) Antibody
Human
ELISA, IF, WB
Unconjugated
100 µl/$435
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KLHL22 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$341
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KLHL22 Rabbit anti-Human Polyclonal (aa586-614) Antibody
Mouse, Human
ELISA, WB
Unconjugated
200 µl/$734
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KLHL22 Rabbit anti-Human Polyclonal (aa586-614) (Biotin) Antibody
Mouse, Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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KLHL22 Rabbit anti-Human Polyclonal (aa586-614) (FITC) Antibody
Mouse, Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
KLHL22 Rabbit anti-Human Polyclonal (aa586-614) (PE) Antibody
Mouse, Human
ELISA, WB
PE Conjugated
200 µl/$952
Select
KLHL22 Rabbit anti-Human Polyclonal (aa586-614) (APC) Antibody
Mouse, Human
ELISA, WB
APC Conjugated
200 µl/$952
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KLHL22 Rabbit anti-Human Polyclonal (aa586-614) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
KLHL22 Antibody - Western blot. All lanes: KLHL22 antibody at 8 ug/ml. Lane 1: Jurkat whole cell lysate. Lane 2: NIH/3T3 whole cell lysate. Secondary antibody: Goat polyclonal to Rabbit IgG at 1:10000 dilution. Predicted band size: 72 kDa. Observed band size: 72 kDa.
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KLHL22 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$294; 100 µg/$360
Select
KLHL22 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
KLHL22 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
KLHL22 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
KLHL22 Antibody - KLHL22 antibody Western blot of Jurkat lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KLHL22 Rabbit anti-Human Polyclonal (aa175-224) Antibody
Human
WB
Unconjugated
100 µl/$424
KLHL22 Antibody - KLHL22 antibody Western blot of Jurkat lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KLHL22 Rabbit anti-Human Polyclonal (aa175-224) (HRP) Antibody
Mouse, Dog, Bovine, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey
WB
HRP Conjugated
100 µl/$469
KLHL22 Antibody - KLHL22 antibody Western blot of Jurkat lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KLHL22 Rabbit anti-Human Polyclonal (aa175-224) (Biotin) Antibody
Mouse, Dog, Bovine, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
KLHL22 Antibody - KLHL22 antibody Western blot of Jurkat lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KLHL22 Rabbit anti-Human Polyclonal (aa175-224) (FITC) Antibody
Mouse, Dog, Bovine, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey
WB
FITC Conjugated
100 µl/$469
KLHL22 Antibody - KLH22 Antibody western blot of HeLa cell line lysates (35 ug/lane). The KLH22 antibody detected the KLH22 protein (arrow).
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KLHL22 Rabbit anti-Human Polyclonal (aa586-614) Antibody
Mouse, Human
WB
Unconjugated
400 µl/$393
Viewing 1-19 of 19 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).