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KLHL21

Kelch-like family member 21

Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for efficient chromosome alignment and cytokinesis. The BCR(KLHL21) E3 ubiquitin ligase complex regulates localization of the chromosomal passenger complex (CPC) from chromosomes to the spindle midzone in anaphase and mediates the ubiquitination of AURKB. Ubiquitination of AURKB by BCR(KLHL21) E3 ubiquitin ligase complex may not lead to its degradation by the proteasome.

Gene Name:	Kelch-like family member 21
Synonyms:	KLHL21
Target Sequences:	NM_014851 NP_055666.2 Q9UJP4

KLHL21 Protein - 12.5% SDS-PAGE of human KLHL21 stained with Coomassie Blue

Human KLHL21 Protein (Recombinant GST) (Full Length) - LS-G31843

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

93 kDa

Price:

10 µg/$479; 25 µg/$670

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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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