KITLG / SCF

KIT ligand

Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. Promotes phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1. KITLG/SCF and KIT also transmit signals via GRB2 and activation of RAS, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. KITLG/SCF and KIT promote activation of STAT family members STAT1, STAT3 and STAT5. KITLG/SCF and KIT promote activation of PLCG1, leading to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate. KITLG/SCF acts synergistically with other cytokines, probably interleukins.

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Products

Proteins (52)

Type

Over-Expression Lysate (4)

Recombinant (48)

Target

KITLG / SCF (52)

Format

Animal-free (3)

Publications

No (52)

Tag

6His, C-terminus (5)

GST (2)

GST, N-terminus (1)

His (4)

His, N-Terminal (2)

His,C-terminus (3)

Human IgG1 Fc (1)

Human Mutant IgG1 Fc (1)

Mouse IgG1 Fc (1)

Mouse IgG2 Fc (2)

Mouse Mutant IgG2a Fc (1)

Myc-DDK (Flag) (4)

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Species

Human (25)

Mouse (14)

Pig (2)

Rat (9)

Source

293F Cells (1)

293T Cells (2)

CHO Cells (7)

E. coli (27)

HEK 293 Cells (5)

Human Cells (1)

Mammalian Cells (4)

Wheat Germ Extract (2)

Yeast (3)

Purification

Purified (18)

Low Endotoxin Level

Low endotoxin level (37)

Biologically Active

Biologically active (21)

Animal-free

Animal-free (3)

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Mouse KITLG / SCF Protein (Recombinant Mouse IgG2 Fc) (aa26-214) - LS-G4137

Source:

CHO Cells

Tag:

Mouse IgG2 Fc

Endotoxin Level:

Less than 0.06 EU/µg protein (determined by LAL method).

Price:

50 µg/$393

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Mouse KITLG / SCF Protein (Recombinant Mouse Mutant IgG2a Fc) (aa26-214) - LS-G4154

Source:

CHO Cells

Tag:

Mouse Mutant IgG2a Fc

Endotoxin Level:

Less than 0.06 EU/µg protein (determined by LAL method).

Price:

50 µg/$393

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Human KITLG / SCF Protein (Recombinant) - LS-G136835

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

18.4 kDa

Price:

50 µg/$391; 10 µg/$294; 1 mg/$2,269; 500 µg/$1,540

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Mouse KITLG / SCF Protein (Recombinant) - LS-G137690

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.01 ng/µg (determined by LAL method).

Molecular Weight:

The 165 amino acid N-terminal methionylated recombinant protein has a predicted molecular mass of 18298.0 Da. The DTT-reduced protein migrates at approximately 18 kDa by SDS-PAGE. The non-reduced protein migrates at approximately 14 kDa by SDS-PAGE.

Price:

10 µg/$344; 25 µg/$459; 100 µg/$907; 500 µg/$1,540

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Human KITLG / SCF Protein (Recombinant) - LS-G137689

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.01 ng/µg (determined by LAL method).

Molecular Weight:

The 165 amino acid recombinant protein has a predicted molecular mass of approximately 18.6 kD. The DTT-reduced and non-reduced protein migrate at approximately 20 kD and 18 kD respectively by SDS-PAGE. The N-terminal amino acid is Met.

Price:

10 µg/$352; 25 µg/$497; 100 µg/$907; 500 µg/$1,559

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KITLG / SCF Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G116918

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

27.87 kDa

Price:

100 µg/$494

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Human KITLG / SCF Protein (Recombinant GST) (aa26-189) - LS-G20896

Source:

E. coli

Tag:

GST

Molecular Weight:

45.85 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human KITLG / SCF Protein (Recombinant GST) (Full Length) - LS-G29326

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

54.3 kDa

Price:

10 µg/$479; 25 µg/$670

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Pig KITLG / SCF Protein (Recombinant His) - LS-G23922

Source:

HEK 293 Cells

Tag:

His

Molecular Weight:

20.4 kDa

Price:

10 µg/$347; 50 µg/$682; 100 µg/$1,018

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Mouse KITLG / SCF Protein (Recombinant) - LS-G27080

Source:

Yeast

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.2 EU/µg protein (determined by LAL method).

Molecular Weight:

18.4 kDa (SDS-PAGE)

Price:

50 µg/$364; 10 µg/$296; 1 mg/$1,612

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Human KITLG / SCF Protein (Recombinant GST, N-terminus) (aa26-135) - LS-G59236

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human KITLG / SCF Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78953

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

30.9 kDa

Price:

20 µg/$150

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Human KITLG / SCF Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78954

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

27.87 kDa

Price:

20 µg/$150

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KITLG / SCF Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99206

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

30.9 kDa

Price:

100 µg/$494

Select

Rat KITLG / SCF Protein (Recombinant) - LS-G3712

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.01 ng/µg of protein (Less than 0.1 EU/µg).

Price:

2 µg/$282; 10 µg/$370

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Human KITLG / SCF Protein (Recombinant Human Mutant IgG1 Fc) (aa26-187) - LS-G4097

Source:

CHO Cells

Tag:

Human Mutant IgG1 Fc

Endotoxin Level:

Less than 0.06 EU/µg protein (determined by LAL method).

Price:

50 µg/$393

Select

Human KITLG / SCF Protein (Recombinant) (aa26-189) - LS-G5751

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Molecular Weight:

18.5 kDa

Price:

10 µg/$388; 100 µg/$766; 500 µg/$1,501

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Mouse KITLG / SCF Protein (Recombinant) (aa26-189) - LS-G5857

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Molecular Weight:

18.4 kDa

Price:

10 µg/$388; 100 µg/$766; 500 µg/$1,501

Select

Human KITLG / SCF Protein (Recombinant Mouse IgG2 Fc) (aa26-187) - LS-G4073

Source:

CHO Cells

Tag:

Mouse IgG2 Fc

Endotoxin Level:

Less than 0.06 EU/µg protein (determined by LAL method).

Price:

50 µg/$393

Select

Human KITLG / SCF Protein (Recombinant Human IgG1 Fc) (aa26-187) - LS-G4062

Source:

CHO Cells

Tag:

Human IgG1 Fc

Endotoxin Level:

Less than 0.06 EU/µg protein (determined by LAL method).

Price:

10 µg/$319

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Rat KITLG / SCF Protein (Recombinant Mouse IgG1 Fc) (aa26-209) - LS-G4159

Source:

CHO Cells

Tag:

Mouse IgG1 Fc

Endotoxin Level:

Less than 0.06 EU/µg protein (determined by LAL method).

Price:

50 µg/$389; 10 µg/$312

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Mouse KITLG / SCF Protein (Recombinant) - LS-G213

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.1 ng/µg of protein (less than 1EU/µg).

Molecular Weight:

18.3 kDa

Price:

2 µg/$268; 10 µg/$349

Select

Mouse KITLG / SCF Protein (Recombinant) - LS-G3702

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.01 ng/µg of protein (Less than 0.1 EU/µg).

Price:

2 µg/$281; 10 µg/$369

• Unmodified
• Animal-free

• Unmodified
• Animal-free

Select

Human KITLG / SCF Protein (Recombinant) - LS-G258

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.1 ng/µg of protein (less than 1EU/µg).

Molecular Weight:

18.4 kDa

Price:

2 µg/$268; 10 µg/$349

Select

Human KITLG / SCF Protein (Recombinant) - LS-G3676

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.01 ng/µg of protein (Less than 0.1 EU/µg).

Price:

2 µg/$281; 10 µg/$369

• Unmodified
• Animal-free

• Unmodified
• Animal-free

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