KITLG / SCF

KIT ligand

Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. Promotes phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1. KITLG/SCF and KIT also transmit signals via GRB2 and activation of RAS, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. KITLG/SCF and KIT promote activation of STAT family members STAT1, STAT3 and STAT5. KITLG/SCF and KIT promote activation of PLCG1, leading to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate. KITLG/SCF acts synergistically with other cytokines, probably interleukins.

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Products

Antibodies (67)

ELISA Kits (60)

Proteins (52)

Type

Custom (5)

Development Kit (9)

Over-Expression Lysate (4)

Primary (67)

Recombinant (48)

Sandwich (40)

Sandwich CLIA (6)

Target

KITLG / SCF (179)

Reactivity

Human (58)

Mouse (33)

Rat (31)

Bovine (5)

Canine (1)

Chicken (6)

Chimpanzee (3)

Dog (7)

Gibbon (3)

Goat (3)

Hamster (3)

Horse (3)

Monkey (4)

Pig (7)

Porcine (1)

Rabbit (4)

Sheep (3)

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Application

IHC (16)

IHC-P (11)

WB (61)

Flo (7)

ELISA (30)

ICC (4)

IF (8)

Inhb (1)

Neut (1)

Peptide-ELISA (1)

Host

rabbit (53)

mouse (11)

goat (3)

Product Group

DevKit Core (7)

DevKit DuoPlus (2)

IHCPlus (3)

Isotype

IgG (18)

IgG1 (9)

IgG1,k (1)

Clonality

monoclonal mc (11)

polyclonal pc (56)

Clone

23 (1)

3E10 (1)

hKL12 (1)

OTI5E9 (2)

OTI5F6 (2)

OTI6E5 (2)

Format

1000 Wells (4)

12 x 8-Well Microstrips (6)

200 Wells (3)

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96-Well Strip Plate (34)

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HRP Conjugated (4)

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Epitope

aa24-247 (8)

aa27-259 (8)

aa244-273 (7)

aa180-229 (4)

aa26-190 (2)

aa100-150 (1)

aa201-234 (1)

aa26-214 (1)

aa26-44 (1)

Publications

No (178)

Yes (1)

Sample Type

Cell Culture Supernatants (17)

Cell Lysates (12)

Plasma (47)

Serum (47)

Tissue Homogenates (18)

Tag

6His, C-terminus (5)

GST (2)

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His (4)

His, N-Terminal (2)

His,C-terminus (3)

Human IgG1 Fc (1)

Human Mutant IgG1 Fc (1)

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Human (25)

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Source

293F Cells (1)

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CHO Cells (7)

E. coli (27)

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Human Cells (1)

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Wheat Germ Extract (2)

Yeast (3)

Purification

Purified (18)

Low Endotoxin Level

Low endotoxin level (37)

Biologically Active

Biologically active (21)

Animal-free

Animal-free (3)

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IHC-plus™ KITLG / SCF Antibody LS-B5002

(5.0) Rating

(1) Publication(s)

Antibody:

KITLG / SCF Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

0.05 mg/$460

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KITLG / SCF Antibody (aa180-229) LS-B4658

Antibody:

KITLG / SCF Rabbit anti-Human Polyclonal (aa180-229) Antibody

Reactivity:

Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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KITLG / SCF Antibody LS-C104837

Antibody:

KITLG / SCF Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

500 µg/$326

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Monkey KITLG / SCF (Sandwich ELISA) ELISA Kit - LS-F48186

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

31.25 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$728

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KITLG / SCF Antibody (clone 3E10) LS-C197679

Antibody:

KITLG / SCF Mouse anti-Human Monoclonal (3E10) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

100 µg/$423

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KITLG / SCF Antibody LS-C87116

Antibody:

KITLG / SCF Rabbit anti-Mouse Polyclonal Antibody

Reactivity:

Mouse

Applications:

Inhb

Format:

Unconjugated

Price:

50 µg/$397; 100 µg/$449

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KITLG / SCF Antibody (aa244-273) LS-C98238

Antibody:

KITLG / SCF Rabbit anti-Human Polyclonal (aa244-273) Antibody

Reactivity:

Human

Applications:

Flo, IF, WB

Format:

Unconjugated

Price:

400 µl/$393

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Bovine KITLG / SCF (Sandwich ELISA) ELISA Kit - LS-F5989

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Bovine

Range:

15.63 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$889

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KITLG / SCF Antibody LS-C104783

Antibody:

KITLG / SCF Rabbit anti-Mouse Polyclonal Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$356; 100 µg/$396

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KITLG / SCF Antibody (clone hKL12) LS-C96331

Antibody:

KITLG / SCF Mouse anti-Human Monoclonal (hKL12) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

200 µg/$783

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KITLG / SCF Antibody (Biotin) LS-C104672

Antibody:

KITLG / SCF Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

25 µg/$356; 50 µg/$396

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KITLG / SCF Antibody (aa24-247, FITC) LS-C304901

Antibody:

KITLG / SCF Rabbit anti-Mouse Polyclonal (aa24-247) (FITC) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$295; 200 µl/$331; 500 µl/$450; 1 ml/$510; 2 ml/$646; 5 ml/$1,098

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IHC-plus™ KITLG / SCF Antibody LS-B8209

(4.0) Rating

Antibody:

KITLG / SCF Goat anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$485

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KITLG / SCF Antibody LS-C662078

Antibody:

KITLG / SCF Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

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KITLG / SCF Antibody (aa244-273) LS-C330650

Antibody:

KITLG / SCF Rabbit anti-Human Polyclonal (aa244-273) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IF, WB

Format:

Unconjugated

Price:

200 µl/$734

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KITLG / SCF Antibody (aa244-273, Biotin) LS-C529304

Antibody:

KITLG / SCF Rabbit anti-Human Polyclonal (aa244-273) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IF, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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KITLG / SCF Antibody (aa244-273, FITC) LS-C282505

Antibody:

KITLG / SCF Rabbit anti-Human Polyclonal (aa244-273) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, ICC, IF, WB

Format:

FITC Conjugated

Price:

200 µl/$952

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KITLG / SCF Antibody (aa244-273, PE) LS-C282506

Antibody:

KITLG / SCF Rabbit anti-Human Polyclonal (aa244-273) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, ICC, IF, WB

Format:

PE Conjugated

Price:

200 µl/$952

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KITLG / SCF Antibody (aa244-273, Azide-free, HRP) LS-C282507

Antibody:

KITLG / SCF Rabbit anti-Human Polyclonal (aa244-273) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, ICC, IF, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

KITLG / SCF Antibody (aa244-273, APC) LS-C282504

Antibody:

KITLG / SCF Rabbit anti-Human Polyclonal (aa244-273) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, ICC, IF, WB

Format:

APC Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• PE
• HRP, Azide-free
• APC

• Unconjugated
• Biotin
• FITC
• More...
  • PE
  • HRP, Azide-free
  • APC

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KITLG / SCF Antibody (clone OTI5F6) LS-C338420

Antibody:

KITLG / SCF Mouse anti-Human Monoclonal (OTI5F6) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$434

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Rat KITLG / SCF (CLIA) ELISA Kit - LS-F49325

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Rat

Range:

7.813 - 500 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$728

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Chicken KITLG / SCF (Sandwich ELISA) ELISA Kit - LS-F23687

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Chicken

Range:

31.25 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$728

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Human KITLG / SCF Protein (Recombinant) - LS-G136835

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

18.4 kDa

Price:

50 µg/$391; 10 µg/$294; 1 mg/$2,269; 500 µg/$1,540

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Mouse KITLG / SCF Protein (Recombinant Mouse IgG2 Fc) (aa26-214) - LS-G4137

Source:

CHO Cells

Tag:

Mouse IgG2 Fc

Endotoxin Level:

Less than 0.06 EU/µg protein (determined by LAL method).

Price:

50 µg/$393

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