KIR2DS4

killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response.

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Products

Antibodies (17)

ELISA Kits (2)

Proteins (2)

Type

Custom (1)

Primary (17)

Recombinant (2)

Sandwich (1)

Target

KIR2DS4 (21)

Reactivity

Human (19)

Application

IHC (4)

IHC-P (2)

WB (16)

Flo (2)

ELISA (3)

IF (2)

Host

rabbit (14)

mouse (3)

Isotype

IgG (5)

IgG2a (2)

IgG2b (1)

Clonality

monoclonal mc (3)

polyclonal pc (14)

Clone

5F2 (1)

Format

96-Well Strip Plate (2)

APC (1)

APC Conjugated (2)

Biotin Conjugated (1)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (1)

HRP Conjugated (1)

PE Conjugated (1)

Unconjugated (9)

Epitope

aa22-302 (8)

aa22-245 (1)

Publications

No (21)

Sample Type

Cell Culture Supernatants (1)

Cell Lysates (1)

Tissue Homogenates (1)

Tag

His (1)

Species

Human (2)

Source

E. coli (2)

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KIR2DS4 Antibody LS-C71391

Antibody:

KIR2DS4 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

Flo, WB

Format:

Unconjugated

Price:

500 µg/$1,089

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Human KIR2DS4 Protein (Recombinant) - LS-G3484

Source:

E. coli

Tag:

None

Price:

100 µg/$411; 500 µg/$985; 20 µg/$276

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KIR2DS4 Antibody (aa22-245) LS-C376007

Antibody:

KIR2DS4 Rabbit anti-Human Polyclonal (aa22-245) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

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KIR2DS4 Antibody LS-C408353

Antibody:

KIR2DS4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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KIR2DS4 Antibody LS-C753886

Antibody:

KIR2DS4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

100 µg/$351

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KIR2DS4 Antibody LS-C155341

Antibody:

KIR2DS4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$450

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KIR2DS4 Antibody LS-C341710

Antibody:

KIR2DS4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

50 µl/$356; 100 µl/$461

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KIR2DS4 Antibody (clone 5F2) LS-C93762

Antibody:

KIR2DS4 Mouse anti-Human Monoclonal (5F2) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µl/$303; 100 µl/$365

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KIR2DS4 Antibody (aa22-302) LS-C295033

Antibody:

KIR2DS4 Rabbit anti-Human Polyclonal (aa22-302) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$303; 200 µl/$343; 500 µl/$476; 1 ml/$543; 2 ml/$715; 5 ml/$1,182

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KIR2DS4 Antibody (aa22-302, HRP) LS-C709908

Antibody:

KIR2DS4 Rabbit anti-Human Polyclonal (aa22-302) (HRP) Antibody

Reactivity:

Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$331; 200 µl/$383; 500 µl/$556; 1 ml/$665; 2 ml/$901; 5 ml/$1,511

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KIR2DS4 Antibody (aa22-302, Biotin) LS-C686053

Antibody:

KIR2DS4 Rabbit anti-Human Polyclonal (aa22-302) (Biotin) Antibody

Reactivity:

Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$313; 200 µl/$357; 500 µl/$503; 1 ml/$576; 2 ml/$788; 5 ml/$1,279

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KIR2DS4 Antibody (aa22-302, FITC) LS-C692650

Antibody:

KIR2DS4 Rabbit anti-Human Polyclonal (aa22-302) (FITC) Antibody

Reactivity:

Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$341; 200 µl/$397; 500 µl/$583; 1 ml/$715; 2 ml/$953; 5 ml/$1,628

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KIR2DS4 Antibody (aa22-302, APC, Cy7) LS-C732960

Antibody:

KIR2DS4 Rabbit anti-Human Polyclonal (aa22-302) (APC, Cy7) Antibody

Reactivity:

Human

Applications:

WB

Format:

APC, Cy7 Conjugated

Price:

100 µl/$489; 200 µl/$614; 500 µl/$1,108; 1 ml/$1,329; 2 ml/$1,860; 5 ml/$3,487

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KIR2DS4 Antibody (aa22-302, APC) LS-C716977

Antibody:

KIR2DS4 Rabbit anti-Human Polyclonal (aa22-302) (APC) Antibody

Reactivity:

Human

Applications:

WB

Format:

APC Conjugated

Price:

100 µl/$396; 200 µl/$476; 500 µl/$815; 1 ml/$969; 2 ml/$1,240; 5 ml/$2,325

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KIR2DS4 Antibody (aa22-302, Cy3) LS-C700885

Antibody:

KIR2DS4 Rabbit anti-Human Polyclonal (aa22-302) (Cy3) Antibody

Reactivity:

Human

Applications:

WB

Format:

Cy3 Conjugated

Price:

100 µl/$396; 200 µl/$476; 500 µl/$815; 1 ml/$969; 2 ml/$1,240; 5 ml/$2,325

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KIR2DS4 Antibody (aa22-302, PE) LS-C723969

Antibody:

KIR2DS4 Rabbit anti-Human Polyclonal (aa22-302) (PE) Antibody

Reactivity:

Human

Applications:

WB

Format:

PE Conjugated

Price:

100 µl/$396; 200 µl/$476; 500 µl/$815; 1 ml/$969; 2 ml/$1,240; 5 ml/$2,325

• Unconjugated
• HRP
• Biotin
• FITC
• APC, Cy7
• APC
• Cy3
• More...
  • PE

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • APC, Cy7
  • APC
  • Cy3
  • PE

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KIR2DS4 Antibody (APC) LS-C71392

Antibody:

KIR2DS4 Mouse anti-Human Monoclonal (APC) Antibody

Reactivity:

Human

Applications:

Flo

Format:

APC Conjugated

Price:

100 Tests/$824

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KIR2DS4 Antibody LS-C772426

Antibody:

KIR2DS4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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Human KIR2DS4 (Custom) ELISA Kit - LS-F66019

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Human

Price:

1 Plate/$783

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Human KIR2DS4 Protein (Recombinant His) (aa22-302) - LS-G13994

Source:

E. coli

Tag:

His

Molecular Weight:

32.1 kDa

Price:

10 µg/$266; 50 µg/$350; 100 µg/$557; 200 µg/$697; 1 mg/$1,716; 500 µg/$1,291; 5 mg/$2,666; 2 mg/$1,893

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Human KIR2DS4 (Sandwich ELISA) ELISA Kit - LS-F8824

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

1.56 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Tissue Homogenates

Price:

1 Plate/$798

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