KIR2DL3 / CD152B2

killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response.

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Products

Proteins (6)

Type

Recombinant (6)

Target

KIR2DL3 / CD152B2 (6)

Publications

No (6)

Tag

6His, C-terminus (1)

Fc, C-terminus (2)

GST (1)

His-GST (1)

Species

Human (6)

Source

E. coli (2)

Human Cells (2)

Mammalian Cells (1)

Wheat Germ Extract (1)

Purification

Purified (1)

Low Endotoxin Level

Low endotoxin level (3)

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Human KIR2DL3 / CD152B2 Protein (Recombinant His-GST) (aa22-342) - LS-G15338

Source:

E. coli

Tag:

His-GST

Molecular Weight:

67.3 kDa

Price:

10 µg/$286; 50 µg/$472; 100 µg/$752; 200 µg/$942; 1 mg/$2,069; 500 µg/$1,600; 5 mg/$3,291; 2 mg/$2,257

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Human KIR2DL3 / CD152B2 Protein (Recombinant GST) (Full Length) - LS-G29126

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

64.3 kDa

Price:

2 µg/$439

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Human KIR2DL3 / CD152B2 Protein (Recombinant Fc, C-terminus) (His22-His245) - LS-G40257

Source:

Human Cells

Tag:

Fc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

51.7kD

Price:

10 µg/$281; 50 µg/$395; 500 µg/$1,585; 1 mg/$2,157

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Human KIR2DL3 / CD152B2 Protein (Recombinant 6His, C-terminus) (His22-His245) - LS-G40256

Source:

Human Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

25.4kD

Price:

10 µg/$281; 50 µg/$395; 500 µg/$1,585; 1 mg/$2,157

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Human KIR2DL3 / CD152B2 Protein (Recombinant Fc, C-terminus) (His22-His245) - LS-G139107

Source:

Mammalian Cells

Tag:

Fc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

51.7 kDa

Price:

10 µg/$281; 50 µg/$389

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Human KIR2DL3 / CD152B2 Protein (Recombinant) - LS-G3485

Source:

E. coli

Tag:

None

Price:

100 µg/$411; 500 µg/$985; 20 µg/$276

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