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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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KIR2DL2 / CD158b

killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response.

Gene Name: killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2
Family/Subfamily: Immunoglobulin , not assigned-Immunoglobulin
Synonyms: KIR2DL2, CD158B1, Cl-43, CD158k, MHC class I NK cell receptor, NKAT6, NKAT-6, p58 NK receptor CL-43, p58.2, CD158b, CD158b1 antigen
Target Sequences: NM_014219 NP_055034.2 P43627

Filtered By: None
Target
KIR2DL2 / CD158b (26)
Reactivity
Human (26)
Mouse (2)
Rat (2)
Application
IHC (8)
WB (19)
Flo (15)
ELISA (7)
IP (7)
Host
rabbit (19)
mouse (7)
Isotype
IgG (15)
IgG1 (7)
Clonality
monoclonal mc (7)
polyclonal pc (19)
Format
AP Conjugated (2)
APC (1)
APC Conjugated (2)
Azide-free (1)
Biotin Conjugated (3)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (3)
HRP Conjugated (3)
MaxLight 405 Conjugated (1)
PE Conjugated (3)
Unconjugated (7)
Epitope
aa22-348 (8)
aa263-291 (8)
Extracellular Domain (1)
Internal (1)
aa304-333 (1)
Publications
No (26)
Showing 1-25 of 26 results

KIR2DL2 / CD158b Antibody (aa263-291) LS-C329733
Rabbit Polyclonal (IgG) to Human KIR2DL2 / CD158b
Human
ELISA Flo WB
Unconjugated
200µl  $530.00

KIR2DL2 / CD158b Antibody (aa263-291, Biotin) LS-C215419
Rabbit Polyclonal (IgG) to Human KIR2DL2 / CD158b
Human
ELISA Flo WB
Biotin Conjugated
200µl  $680.00

KIR2DL2 / CD158b Antibody (aa263-291, FITC) LS-C215421
Rabbit Polyclonal (IgG) to Human KIR2DL2 / CD158b
Human
ELISA Flo WB
FITC Conjugated
200µl  $680.00

KIR2DL2 / CD158b Antibody (aa263-291, AP) LS-C215418
Rabbit Polyclonal (IgG) to Human KIR2DL2 / CD158b
Human
ELISA Flo WB
AP Conjugated
200µl  $680.00

KIR2DL2 / CD158b Antibody (aa263-291, Azide-free, HRP) LS-C215422
Rabbit Polyclonal (IgG) to Human KIR2DL2 / CD158b
Human
ELISA Flo WB
HRP Conjugated, Azide-free
200µl  $680.00

KIR2DL2 / CD158b Antibody (aa263-291, PE) LS-C215423
Rabbit Polyclonal (IgG) to Human KIR2DL2 / CD158b
Human
ELISA Flo WB
PE Conjugated
200µl  $680.00

KIR2DL2 / CD158b Antibody (aa263-291, APC) LS-C215420
Rabbit Polyclonal (IgG) to Human KIR2DL2 / CD158b
Human
ELISA Flo WB
APC Conjugated
200µl  $680.00

KIR2DL2 / CD158b Antibody (Extracellular Domain) LS-C21983
Mouse Monoclonal (IgG1) to Human KIR2DL2 / CD158b
Human
Flo IP
Unconjugated
200µg 1mg/ml  $710.00

KIR2DL2 / CD158b Antibody (HRP) LS-C544884
Mouse Monoclonal (IgG1) to Human KIR2DL2 / CD158b
Human
Flo IP
HRP Conjugated
100µl  $905.00

KIR2DL2 / CD158b Antibody (Biotin) LS-C524757
Mouse Monoclonal (IgG1) to Human KIR2DL2 / CD158b
Human
Flo IP
Biotin Conjugated
100µl  $905.00

KIR2DL2 / CD158b Antibody (FITC) LS-C534778
Mouse Monoclonal (IgG1) to Human KIR2DL2 / CD158b
Human
Flo IP
FITC Conjugated
100µl  $905.00

KIR2DL2 / CD158b Antibody (MaxLight 405) LS-C563671
Mouse Monoclonal (IgG1) to Human KIR2DL2 / CD158b
Human
Flo IP
MaxLight 405 Conjugated
100µl 1.3mg/ml  $905.00

KIR2DL2 / CD158b Antibody (PE) LS-C652965
Mouse Monoclonal (IgG1) to Human KIR2DL2 / CD158b
Human
Flo IP
PE Conjugated
100µl  $905.00

KIR2DL2 / CD158b Antibody (aa22-348) LS-C295032
Rabbit Polyclonal (IgG) to Human KIR2DL2 / CD158b
Human
IHC WB
Unconjugated
20µl 0.5mg/ml  $205.00; 100µl 0.5mg/ml  $255.00; 200µl 0.5mg/ml  $305.00; 1ml 0.5mg/ml  $530.00; 10ml 0.5mg/ml  $2,100.00
Western blot of recombinant KIR2DL2 / CD158b.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of recombinant KIR2DL2 / CD158b.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

KIR2DL2 / CD158b Antibody (aa22-348, HRP) LS-C712691
Rabbit Polyclonal (IgG) to Human KIR2DL2 / CD158b
Human
IHC WB
HRP Conjugated
20µl  $215.00; 100µl  $285.00; 200µl  $345.00; 1ml  $680.00; 10ml  $2,730.00
Western blot of recombinant KIR2DL2 / CD158b.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of recombinant KIR2DL2 / CD158b.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

KIR2DL2 / CD158b Antibody (aa22-348, Biotin) LS-C297053
Rabbit Polyclonal (IgG) to Human KIR2DL2 / CD158b
Human
IHC WB
Biotin Conjugated
100µl 0.5mg/ml  $425.00
Western blot of recombinant KIR2DL2 / CD158b.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of recombinant KIR2DL2 / CD158b.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

KIR2DL2 / CD158b Antibody (aa22-348, FITC) LS-C303107
Rabbit Polyclonal (IgG) to Human KIR2DL2 / CD158b
Human
IHC WB
FITC Conjugated
100µl 0.5mg/ml  $455.00
Western blot of recombinant KIR2DL2 / CD158b.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of recombinant KIR2DL2 / CD158b.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

KIR2DL2 / CD158b Antibody (aa22-348, APC) LS-C718412
Rabbit Polyclonal (IgG) to Human KIR2DL2 / CD158b
Human
IHC WB
APC Conjugated
20µl  $225.00; 100µl  $305.00; 200µl  $375.00; 1ml  $785.00; 10ml  $6,180.00
Western blot of recombinant KIR2DL2 / CD158b.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of recombinant KIR2DL2 / CD158b.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

KIR2DL2 / CD158b Antibody (aa22-348, Cy3) LS-C703669
Rabbit Polyclonal (IgG) to Human KIR2DL2 / CD158b
Human
IHC WB
Cy3 Conjugated
20µl  $245.00; 100µl  $355.00; 200µl  $445.00; 1ml  $1,050.00; 10ml  $4,200.00
Western blot of recombinant KIR2DL2 / CD158b.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of recombinant KIR2DL2 / CD158b.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

KIR2DL2 / CD158b Antibody (aa22-348, PE) LS-C726752
Rabbit Polyclonal (IgG) to Human KIR2DL2 / CD158b
Human
IHC WB
PE Conjugated
20µl  $215.00; 100µl  $275.00; 200µl  $325.00; 1ml  $635.00; 10ml  $2,520.00
Western blot of recombinant KIR2DL2 / CD158b.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of recombinant KIR2DL2 / CD158b.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

KIR2DL2 / CD158b Antibody (aa22-348, APC, Cy7) LS-C735678
Rabbit Polyclonal (IgG) to Human KIR2DL2 / CD158b
Human
IHC WB
APC, Cy7 Conjugated
20µl  $285.00; 100µl  $455.00; 200µl  $635.00; 1ml  $1,575.00; 10ml  $6,300.00
Western blot of recombinant KIR2DL2 / CD158b.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of recombinant KIR2DL2 / CD158b.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

KIR2DL2 / CD158b Antibody (aa304-333) LS-C165525
Rabbit Polyclonal to Human KIR2DL2 / CD158b
Human
Flo WB
Unconjugated
50µg  $250.00
KIR2DL2 Antibody (C-term) Western blot analysis in HL-60 cell line lysates (15 ug/lane). This demonstrates the KIR2DL2 antibody detected the KIR2DL2 protein (arrow).
KIR2DL2 Antibody (C-term) flow cytometric analysis of HL-60 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
KIR2DL2 Antibody (C-term) Western blot analysis in HL-60 cell line lysates (15 ug/lane). This demonstrates the KIR2DL2 antibody detected the KIR2DL2 protein (arrow).
KIR2DL2 Antibody (C-term) flow cytometric analysis of HL-60 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

KIR2DL2 / CD158b Antibody (aa263-291) LS-C165526
Rabbit Polyclonal to Human KIR2DL2 / CD158b
Human
Flo WB
Unconjugated
400µl  $305.00
KIR2DL2 Antibody western blot of MDA-MB231,Jurkat cell line lysates (35 ug/lane). The KIR2DL2 antibody detected the KIR2DL2 protein (arrow).
KIR2DL2 Antibody flow cytometry of MDA-MB231 cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
KIR2DL2 Antibody western blot of MDA-MB231,Jurkat cell line lysates (35 ug/lane). The KIR2DL2 antibody detected the KIR2DL2 protein (arrow).
KIR2DL2 Antibody flow cytometry of MDA-MB231 cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

KIR2DL2 / CD158b Antibody LS-C340985
Rabbit Polyclonal to Human KIR2DL2 / CD158b
Mouse, Rat, Human
WB
Unconjugated
100µl 1mg/ml  $385.00

KIR2DL2 / CD158b Antibody (Internal) LS-C352420
Rabbit Polyclonal to Human KIR2DL2 / CD158b
Mouse, Rat, Human
WB
Unconjugated
100µl 1mg/ml  $245.00
Western blot analysis of CD158b1 expression in MDAMB231 (A); Jurkat (B); mouse liver (C); H9C2 (D) whole cell lysates.
Western blot analysis of CD158b1 expression in MDAMB231 (A); Jurkat (B); mouse liver (C); H9C2 (D) whole cell lysates.
Showing 1-25 of 26 results

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PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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