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KIF2A

kinesin heavy chain member 2A

Plus end-directed microtubule-dependent motor required for normal brain development. May regulate microtubule dynamics during axonal growth. Required for normal progression through mitosis. Required for normal congress of chromosomes at the metaphase plate. Required for normal spindle dynamics during mitosis. Promotes spindle turnover. Implicated in formation of bipolar mitotic spindles. Has microtubule depolymerization activity.

Gene Name: kinesin heavy chain member 2A
Synonyms: KIF2A, KNS2, KIF2, Kinesin heavy chain member 2A, Kinesin heavy chain member 2, Kinesin, heavy chain, 2, Kinesin-like protein KIF2A, Kinesin-2
Target Sequences: NM_004520 NP_004511.2 O00139

Publications (4)

1
Prophase microtubule arrays undergo flux-like behavior in mammalian cells. Ferenz NP, Wadsworth P. Molecular biology of the cell. 2007 18:3993-4002. [PubMed:17671163] [PMC:PMC1995704]
2
DDA3 recruits microtubule depolymerase Kif2a to spindle poles and controls spindle dynamics and mitotic chromosome movement. Jang CY, Wong J, Coppinger JA, Seki A, Yates JR, Fang G. The Journal of cell biology. 2008 181:255-67. [PubMed:18411309] [PMC:PMC2315673]
3
Plk1 and Aurora A regulate the depolymerase activity and the cellular localization of Kif2a. Jang CY, Coppinger JA, Seki A, Yates JR, Fang G. Journal of cell science. 2009 122:1334-41. [PubMed:19351716] [PMC:PMC2671931]
4
Poleward transport of TPX2 in the mammalian mitotic spindle requires dynein, Eg5, and microtubule flux. Ma N, Tulu US, Ferenz NP, Fagerstrom C, Wilde A, Wadsworth P. Molecular biology of the cell. 2010 21:979-88. (ICC; Pig) [PubMed:20110350] [PMC:PMC2836978]
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Products
Antibodies (38)
Primary (38)
KIF2A (38)
Human (38)
Mouse (13)
Rat (19)
Bat (6)
Bovine (9)
Chicken (6)
Chimpanzee (6)
Dog (6)
Gibbon (6)
Guinea pig (6)
Horse (9)
Mammal (1)
Monkey (6)
Orangutan (6)
Pig (4)
Rabbit (6)
Xenopus (6)
IHC (15)
IHC-P (6)
WB (31)
ELISA (14)
IF (1)
IP (3)
rabbit (32)
mouse (6)
Product Group
IHCPlus (2)
IgG (14)
IgG1,k (6)
monoclonal mc (6)
polyclonal pc (32)
2D4 (1)
APC (1)
APC Conjugated (2)
Biotin Conjugated (6)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (6)
HRP Conjugated (6)
PE Conjugated (2)
Unconjugated (14)
aa1-254 (8)
C-Terminus (4)
aa578-627 (4)
aa72-121 (4)
N-Terminus (2)
aa630-679 (1)
No (38)
KIF2A Antibody - Anti-KIF2A antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:500.
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KIF2A Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Rat, Pig, Mammal, Human
IHC, IHC-P
Unconjugated
0.1 ml/$460
KIF2A Antibody - Anti-KIF2A antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KIF2A Rabbit anti-Human Polyclonal (aa72-121) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
KIF2A Antibody - Anti-KIF2A antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KIF2A Rabbit anti-Human Polyclonal (aa72-121) (HRP) Antibody
Mouse, Bovine, Horse, Human
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
KIF2A Antibody - Anti-KIF2A antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KIF2A Rabbit anti-Human Polyclonal (aa72-121) (Biotin) Antibody
Mouse, Bovine, Horse, Human
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
KIF2A Antibody - Anti-KIF2A antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KIF2A Rabbit anti-Human Polyclonal (aa72-121) (FITC) Antibody
Mouse, Bovine, Horse, Human
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
KIF2A Antibody - HepG2 cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KIF2A Rabbit anti-Human Polyclonal (aa578-627) Antibody
Human
WB
Unconjugated
100 µl/$424
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KIF2A Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IP, WB
Unconjugated
100 µg/$331
KIF2A Antibody - Immunohistochemistry of paraffin-embedded Human tonsil tissue  using KIF2A Polyclonal Antibody at dilution of 1:65(×200)
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KIF2A Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
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KIF2A Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IF, IP, WB
Unconjugated
100 µl/$649
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KIF2A Mouse anti-Human Monoclonal (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated
100 µl/$904
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KIF2A Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
100 µl/$904
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KIF2A Mouse anti-Human Monoclonal (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
100 µl/$904
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KIF2A Mouse anti-Human Monoclonal (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
100 µl/$904
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KIF2A Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
100 µl/$904
KIF2A Antibody - Immunohistochemistry of paraffin-embedded human lymph node tissue at dilution of 1:100
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KIF2A Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
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KIF2A Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
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KIF2A Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
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KIF2A Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
KIF2A Antibody - Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue  using KIF2A Polyclonal Antibody at dilution of 1:55(×200)
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KIF2A Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
KIF2A Antibody - Immunohistochemistry of paraffin-embedded Human breast cancer using KIF2A Polyclonal Antibody at dilution of 1:30.
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KIF2A Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
KIF2A Antibody - Detection limit for recombinant GST tagged KIF2 is approximately 0.1 ng/ml as a capture antibody.
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KIF2A Mouse anti-Human Monoclonal (2D4) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
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KIF2A Rabbit anti-Human Polyclonal (aa630-679) Antibody
Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
KIF2A Antibody - KIF2A antibody Western blot of 721_B cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KIF2A Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
KIF2A Antibody - Western blot analysis of extracts of rat brain using KIF2A Polyclonal Antibody at dilution of 1:1000.
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KIF2A Rabbit anti-Human Polyclonal Antibody
Rat, Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
KIF2A Antibody - Western blot of KIF2A antibody.
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KIF2A Rabbit anti-Human Polyclonal (aa1-254) Antibody
Rat, Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
Viewing 1-25 of 38 product results


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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).